AUA 2021

Prostate Cancer Screenings Fell Sharply Early in COVID-19 Pandemic

The decrease in prostate cancer screening rates was the smallest among 5 cancers studied.

Older Adults May Benefit From NAC Prior to UTUC Radical Surgery

Neoadjuvant chemotherapy prior to radical nephroureterectomy for upper tract urothelial carcinoma may improve pathologic outcomes regardless of age, new data suggest.

CKD Associated With Worse Radical Cystectomy Outcomes

Investigators report increased risks for adverse pathology and 90-day readmission.

Plant-Based Diets Tied to Lower Risk for Aggressive Prostate Cancer

Greater consumption of healthful plant-based foods is associated with significantly reduced risks for advanced, lethal, and fatal prostate cancer, especially among men younger than 65 years.

Obesity Ups Survival in Metastatic Castration-Resistant Prostate Cancer

The protective effect of high body mass index is not related to use of higher doses of chemotherapy, investigators reported.

Primary Chemoablation for Low-Grade Intermediate-Risk NMIBC Promising

A mitomycin-containing reverse thermal gel could provide an alternative to repetitive surgeries for low-grade intermediate-risk NMIBC, according to investigators.

BCG for Bladder Cancer May Lower Alzheimer Disease Risk

The risk for alzheimer disease decreased with increased dosing of BCG.

Partial, Radical Cystectomy for MIBC Yield Similar Survival Outcomes

In addition to similar rates of overall survival, patients undergoing partial and radical cystectomy had comparable rates of upstaging to pT3-4 disease.

Kidney-Sparing Surgery Offers Effective Oncologic Control in High-Risk UTUC

In this small study, even patients with high-risk tumors appeared to benefit from nephron-sparing surgery.

Metabolic Syndrome Post-Prostatectomy Ups Prostate Cancer Death Risk

The risks for metastasis, biochemical recurrence, and overall mortality are unaffected, according to investigators.

Epigenetic Test May Rule Out High-Grade UTUC

If validated, the EpiCheck® assay may identify more patients who can safely delay or avoid nephroureterectomy.

Lower Post-Nephrectomy Kidney Function May Up ESKD Risk

New study findings “are critically important in patient counseling and surgical planning, particularly for patients with risk factors for renal deterioration,” according to investigators.

Enzalutamide Shown to Slow Progression of Localized Prostate Cancer

A phase 2 exploratory study of men with low- and intermediate-risk localized prostate cancer demonstrated the oncologic benefit of enzalutamide treatment vs active surveillance.

Study: Chest Imaging After RCC Surgery Not Warranted

Investigators concluded that there is minimal to no clinical value in surveillance for pulmonary recurrence after T1a RCC resection.

Neoadjuvant Chemotherapy Underused for MIBC in Older Adults

Older age independently predicted significant 48% lower odds of the gold standard treatment of NAC and radical cystectomy.

Nadofaragene Firadenovec Shows Longer-Term Efficacy in BCG-Unresponsive NMIBC

Study results support an attempt at bladder preservation in patients with BCG-unresponsive nonmuscle-invasive bladder cancer.

Investigators: Consider 5-ARI Use When Deciding on Prostate Biopsy

At prostate cancer diagnosis, clinical T stage was significantly higher among 5-ARI users compared with nonusers.

RCC Subtype Affects Post-Nephrectomy Survival Rates

Five-year survival rates following nephrectomy for renal cell carcinoma are higher among patients with favorable vs unfavorable histology.

Outcomes of BCG-Unresponsive NMIBC Characterized

In a small study, most BCG-unresponsive patients who were initially managed conservatively ultimately underwent cystectomy.