Novel Kinase Inhibitor Shows Efficacy in Patients with Advanced HCC Tumors Overexpressing AFP
LY2157299 monohydrate showed promising efficacy results in patients with advanced HCC tumors overexpressing AFP.
GI Cancers Symposium 2014
CTCs Have High Specificity for Diagnosis of Pancreatic Ductal Adenocarcinoma
Circulating tumor cells are a useful adjunct in the diagnosis of pancreatic ductal adenocarcinoma.
PET/CT Can Prevent ‘Futile Laparotomy’ in Resectable/Borderline Pancreatic Cancer
PET/CT may prevent unnecessary laparotomy by detecting occult metastatic disease in patients with resectable/borderline pancreatic cancer.
Nab-Paclitaxel Plus Gemcitabine Sustains OS in Metastatic Pancreatic Adenocarcinoma
Nab-paclitaxel plus gemcitabine sustained overall survival rates compared with gemcitabine alone in patients with metastatic pancreatic adenocarcinoma.
Cetuximab Does Not Improve FOLFOX4 Outcomes for CRC with RAS Mutations
Cetuximab should not be added to first-line FOLFOX4 for patients whose mCRC harbors RAS mutations.
Cetuximab Does Not Improve Outcomes for Esophageal Cancer Chemoradiation
Cetuximab does not improve overall survival or clinical complete response rates for esophageal cancer chemoradiation.
Risk Factors Should Prompt Endoscopic Screening for High-risk Gastric Cancer
Early detection of high-risk, presymptomatic gastric cancer with endoscopic screening is associated with improved survival.
Everolimus Failed to Improve Survival in Advanced HCC
Data indicate that everolimus did not improve overall survival in patients with advanced HCC following sorafenib failure.
Second-Line Trastuzumab Active in HER2-positive Advanced/Recurrent Gastric Cancer
Second-line treatment with paclitaxel/trastuzumab showed promising activity in trastuzumab-naïve patients with HER2-positive gastric cancer.
Poorer Survival Observed with MET-positive Stage IV Gastric Tumors
Patients with stage IV gastric tumors positive for MET protein expression have poorer survival than those without MET expression.
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