CTC Screening May Be Effective Method for Preventing Colorectal Cancer
Current screening methods have a low sensitivity for precancerous lesions and are inconvenient, leading to high rates of noncompliance.
GI Cancers Symposium 2018
Physical Activity Intervention May Improve Functional Well-being Among CRC Survivors
Survivors assigned to an experimental arm showed an improvement in the FACT-C functional well-being sub-scale from baseline to 12 weeks.
Atezolizumab With Cobimetinib Yields Partial Response in Small Number of Patients With CRC
MEK inhibition with cobimetinib may improve the response rate with checkpoint inhibition.
Nivolumab May Improve Long-term Complete Response Rate in Subset of Patients With mCRC
Researchers treated 74 patients with dMMR/MSI-H mCRC with nivolumab 3 mg/kg every 2 weeks.
Pembrolizumab May Be Effective for Previously Treated Hepatocellular Carcinoma
Researchers evaluated whether the PD-1 inhibitor would improve outcomes among patients with HCC who progressed after sorafenib treatment.
Cabozantinib May Improve Survival Outcomes in Relapsed Hepatocellular Carcinoma
Researchers randomly assigned 707 patients with advanced HCC to receive oral cabozantinib 60 mg once daily or placebo.
PEGPH20 Plus mFOLFIRINOX Worsens OS Among Patients With Pancreatic Cancer
Preclinical models suggested that PEGPH20, which degrades hyaluronan, would improve survival among patients with metastatic pancreatic adenocarcinoma.
Gemcitabine Plus S-1 May Be Non-inferior to Standard Therapy for Biliary Tract Cancer
The study arms had similar rates of adverse events, with 34.7% of patients in the cisplatin arm and 31.2% of patients in the S-1 arm reporting clinically relevant events.
RAMIE May Improve Post-operative Outcomes Among Patients With Esophageal Cancer
Robot-assisted minimally invasive thoraco-laparoscopic esophagectomy may be a lower-cost alternative, with better post-operative outcomes, to open transthoracic esophagectomy.
Extensive Intraoperative Peritoneal Lavage May Not Improve OS in Gastric Cancer
Previous research suggested that EIPL may improve survival by reducing the number of intraperitoneal-free cancer cells.
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