NCCN 2022

Chemo at Home: High Rate of Satisfaction, Low Rate of Discontinuation

Most patients completed at-home chemotherapy infusions as planned, and no one stopped treatment because of adverse drug reactions.

Cancer Incidence and Risk Factors Among Immunocompromised Patients

The cancer incidence in certain immunocompromised patients was almost twice as high as the age-adjusted cancer incidence in the general population.

Real-World Data Support Waiting for Biomarker Testing Results to Start Treatment

Patients who did not receive EGFR TKIs had a significantly higher risk of dying or needing subsequent treatment.

How Pembro-Chemo Compares With Other Treatments for Advanced TNBC

First-line pembrolizumab plus nab-paclitaxel may improve some outcomes over chemotherapy alone in advanced triple-negative breast cancer.

Factors Associated with Late Relapse in Triple-Negative Breast Cancer

Late relapse of triple-negative breast cancer is associated with biological factors but not sociodemographic factors, a study suggests.

Moderna COVID-19 Vaccine May Be More Effective in CLL Patients

Patients with CLL were significantly more likely to have an antibody response to the Moderna vaccine than to the Pfizer-BioNTech vaccine.

Perineural Invasion Linked to Biochemical Recurrence After Prostatectomy

Patients with perineural invasion had a 4-fold higher risk of biochemical recurrence.

Study Supports Reclassification of Cutaneous Squamous Cell Carcinoma

Patients in the very high risk group had a significantly higher risk of recurrence, metastasis, and death.

AML Incidence and Deaths Increasing Worldwide

Although mortality-to-incidence indices are improving globally, the increasing burden of AML is “concerning,” according to researchers.

Timing of Neoadjuvant Chemotherapy May Affect Breast Cancer Recurrence

Recurrence rates were highest among patients who received at least 70% of treatments before noon.

Monoclonal Antibodies Lower Risk of COVID-19 Hospitalization in Cancer Patients

There was no significant difference in post-infusion hospitalizations between patients with and without a history of cancer.

Preventing Unplanned Emergency Department Visits in Cancer Patients

Researchers evaluated the effects of an after-hours nurse triage phone program, extended hours for infusion services, and a cancer-specific urgent care center.

Small-Cell Lung Cancer Patients May Have More Socioeconomic Disadvantages

A greater likelihood of socioeconomic disadvantages may help explain the poor survival outcomes observed in patients with small-cell lung cancer, according to researchers.

Expanding Eligibility for Genetic Testing Reveals Clinically Actionable Variants

Researchers discovered actionable germline genetic variants in 20% of patients who did not meet genetic testing criteria according to prior guidelines.

Warmer Climate Tied to Favorable Breast Cancer Outcomes

Patients living in warmer climates were more likely to achieve a pathologic complete response and had a lower risk of death.