|The following article features coverage from the 2020 San Antonio Breast Cancer Symposium. Click here to read more of Cancer Therapy Advisor‘s conference coverage.|
A retrospective analysis found that women who received silicone breast implants from Poly Implant Prothèse (PIP), a manufacturer in France, did not have an increased risk of breast cancer recurrence or early death.1 The poster findings were reported at the 2020 Virtual San Antonio Breast Cancer Symposium (SABCS).
In 2010, the French Medical Regulatory Authority (ANSM) banned the medical use of silicone breast implants manufactured by PIP when the agency discovered that the French manufacturer was filling the implants with a substandard gel.2
Approximately 30,000 women in France have received breast implants manufactured by PIP since 2001.2
The analysis included 2499 patients from 3 private health institutions in France who collectively received 4106 breast implants between 2002 and 2010. The time period was selected because it corresponded with the entry of PIP-manufactured implants into the French market and removal from the French market.
Nearly half of patients (45%) received an implant manufactured by PIP, and among the patients who received PIP-manufactured implants, 80% of the implants were surgically removed.
PIP-manufactured implants had a significantly lower removal rate than implants manufactured by other companies (P =.001).
No significant difference in overall survival (P =.2) or disease-free survival (P =.12) was seen between patients who had at least 1 implant manufactured by PIP and patients who had an implant from a different manufacturer.
“We did not identify any increase in local-regional recurrence or overall mortality associated with the use of PIP,” the study authors concluded.
Read more of Cancer Therapy Advisor‘s coverage of the 2020 SABCS meeting by visiting the conference page.
- Pauly L, Couturaud B, Reyal F. What lessons can be learned from the Poly Implant Prothese scandal? A French retrospective study. Poster presented at: 2020 Virtual San Antonio Breast Cancer Symposium; December 8-11, 2020. Abstract PS1-65.
- French Medical Regulatory Authority (ANSM). Topical report: PIP silicone gel pre-filled implants. Published June 2011. Accessed December 6, 2020.