Findings Support Retesting for MMRD at Uterine Cancer Recurrence
Patients who have mismatch repair proficiency in the primary setting may have mismatch repair deficiency at recurrence.
Society of Gynecologic Oncology (SGO)
Molecularly Targeted Therapy May Improve Survival in Advanced, Recurrent Endometrial Cancer
In a real-world study, more than 54% of patients had at least 1 potentially actionable genomic alteration.
Prolonging Survival in Patients With Advanced Ovarian Cancer
A subanalysis of the GOG 252 trial revealed factors associated with longer survival among patients with stage II-III epithelial ovarian cancer.
First-Line Niraparib Maintenance Improves PFS in Advanced Ovarian Cancer
Niraparib reduced the risk of progression or death by 55%.
ctDNA May Allow for Earlier Detection of Progression in Ovarian Cancer
In one patient, progression would have been detected up to 143 days earlier with ctDNA than with conventional surveillance methods.
Mirvetuximab Soravtansine: A New Standard of Care in Ovarian Cancer?
The response rate observed with mirvetuximab soravtansine was nearly triple the benchmark set in prior studies.
Risk of Cervical Cancer Recurrence Still 4 Times Higher With Minimally Invasive Surgery
Open radical hysterectomy was associated with better outcomes at a median follow-up of 4.5 years.
MAPK Mutations Linked to Better PFS, OS in Low-Grade Serous Ovarian Carcinoma
The median overall survival was 147.8 months for patients with MAPK-mutated tumors and 89.5 months for patients without MAPK mutations.
Pandemic-Related Burnout Tied to Anxiety, Depression, and PTSD in SGO Members
In the first wave, 59% of respondents met criteria for low professional fulfillment, and 41% met criteria for burnout.
Is First-Line Maintenance Underused in Advanced Ovarian Cancer?
In a study of more than 5000 patients with advanced ovarian cancer, 56% received first-line maintenance therapy.
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