In this study, pre- and postsurgical specimens of cell-free DNA from women with newly diagnosed endometrial cancer were subjected to ultra-high depth sequencing.
The search for molecular precursors of cancer in the fallopian tubes is largely driven by emerging evidence supporting it as the site of origin for many ovarian cancers.
PAOLA-1/ENGOT-ov25 is a phase 3 clinical trial evaluating a first-line olaparib plus bevacizumab maintenance regimen in patients with advanced ovarian cancer.
NCCN Ovarian Cancer Guidelines include a recommendation for somatic and genetic testing following a genetic risk evaluation for all women with the disease.
The insulin-lowering properties of metformin, along with its effects on synthetic metabolism, were some of the rationales for its use as a cancer therapy.
This analysis represents the largest reported series of patients with early-stage vulvar cancer characterized by a negative sentinel lymph node biopsy.