Oral Urinary Tract Infection Treatments
Generic Brand Strength Form Adult Dose Duration
cefadroxil 500mg capsUncomplicated UTI: 1−2g once daily or in 2 divided doses
Complicated UTI: 2g/day in 2 divided doses
1g tabs
250mg/5mL, 500mg/5mL susp
cefixime Suprax 100mg, 150mg, 200mg chew tabs 400mg once daily or 200mg every 12hrs  
200mg/5mL, 500mg/5mL susp
cefpodoxime 50mg/5mL, 100mg/5mL granules for susp 100mg every 12hrs 7 days
100mg, 200mg tabs
cefuroxime 250mg, 500mg tabs 250mg twice daily 7−10 days
cephalexin 250mg, 500mg, 750mg caps 250mg every 6hrs; may give 500mg every 12hrs. Max 4g/day in 2–4 equally divided doses 7−14 days
nitrofurantoin Furadantin 25mg/5mL susp 50−100mg 4 times daily.
Suppressive therapy: 50−100mg once daily at bedtime may suffice
Macrobid 100mg caps 100mg every 12hrs 7 days
25mg, 50mg, 100mg caps 50−100mg 4 times daily.
Long-term use: 50−100mg once daily at bedtime
7 days
amoxicillin 250mg, 500mg caps 500mg every 12hrs or 250mg every 8hrs. Severe infections: 875mg every 12hrs or 500mg every 8hrs.
500mg, 875mg tabs
125mg/5mL, 250mg/5mL susp
amoxicillin/ clavulanic acid 200mg/28.5mg, 400mg/57mg chewable 500mg every 12hrs or 250mg every 8hrs. Severe infections: 875mg every 12hrs or 500mg every 8hrs.
250mg/125mg, 500mg/125mg, 875mg/125mg tabs
Augmentin 875mg/125mg tabs
125mg/31.25mg/ 5mL, 250mg/ 62.5mg/5mL susp
ciprofloxacin Cipro 250mg, 500mg tabs Acute uncomplicated cystitis due to E. coli, S. saprophyticus in females: 250mg every 12hrs. 3 days
250mg/5mL, 500mg/5mL susp
Other UTI: 250−500mg every 12hrs 7−14 days
Cipro XR 500mg, 1000mg ext‑rel tabs Uncomplicated UTI: 500mg once daily 3 days
Complicated UTI, acute uncomplicated pyelonephritis: 1000mg once daily 7−14 days
levofloxacin 25mg/mL soln Uncomplicated UTI: 250mg once daily. Complicated UTI, acute pyelonephritis: 250mg once daily or 750mg once daily 3 days
250mg, 500mg, 750mg tabs 250mg dose: 10 days
750mg dose: 5 days
ofloxacin 200mg, 300mg, 400mg tabs Uncomplicated cystitis: 200mg every 12hrs 3 days (E. coli or K. pneu
); 7 days (other)
Complicated: 200mg every 12hrs 10 days
oxazole/ trimethoprim
200mg/40mg/5mL susp20mL every 12hrs 10−14 days
Bactrim 400mg/80mg tabs 2 tabs every 12hrs
Bactrim DS 800mg/160mg tabs 1 tab every 12hrs
Septra DS
fosfomycin Monurol 3g granules for soln Uncomplicated UTI: Females: Mix 1 sachet with 3−4oz of water (do not use hot water); drink immediately. Max 1 dose/episode. 1 dose
trimethoprim 100mg, 200mg tabs Uncomplicated UTI: 100mg twice daily, or 200mg once daily 10 days

Not an inclusive list of medications. Please see drug monographs at www.eMPR.com and/or contact company for full drug labeling.

(Rev. 5/2022)

This article originally appeared on MPR