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General Oncology Treatment Guidelines in Cancer: Assessing Industry Influence on Recommendations

Treatment Guidelines in Cancer: Assessing Industry Influence on Recommendations

Concerns about conflict of interest as it relates to prescribing may never go away, some say, as long as drug companies offer doctors money for consulting and personal services.

Chronic Myeloid Leukemia Patients With CP-CML Deemed Less Likely to Continue Taking Generic Imatinib

Patients With CP-CML Deemed Less Likely to Continue Taking Generic Imatinib

In a Canadian matched cohort study, intolerance drove patients with CP-CML to switch from generic imatinib at a higher frequency compared with those given brand-name products.

General Oncology Opinion: Understanding the FDA's Take on Cannabidiol

Opinion: Understanding the FDA's Take on Cannabidiol

In a statement announcing a newly created partnership, the Botanical Safety Consortium, FDA Commissioner Scott Gottlieb made no mention of cannabidiol.

Brain Cancer Immunotherapy in Glioblastoma: Peaks and Pits

Immunotherapy in Glioblastoma: Peaks and Pits

New studies in glioblastoma highlight how PD-1 inhibitors could simultaneously prompt an immune response and steer the selection of tumor clones that evade immune recognition.

Prostate Cancer Radical Prostatectomy Compared With Watchful Waiting in Localized Prostate Cancer

Radical Prostatectomy Compared With Watchful Waiting in Localized Prostate Cancer

At 23 years of follow-up, the cumulative incidence of death was higher among patients in the watchful waiting group compared with those in the radical prostatectomy group.

General Oncology Q&A With Mark B. Gerstein, PhD, on Diagnostic Genomic vs Exomic Sequencing

Q&A With Mark B. Gerstein, PhD, on Diagnostic Genomic vs Exomic Sequencing

"People have shown that the variant-identification quality of WGS is superior to WES," said Dr Gerstein.

Renal Cell Carcinoma Immune Signature for Renal Cell Papillary Carcinoma Predicts Outcome

Immune Signature for Renal Cell Papillary Carcinoma Predicts Outcome

Researchers identified 15 genes that they said independently predict the survival outcome of patients with kidney renal papillary cell carcinoma.

General Oncology Patient-Reported Outcomes in Oncology Expected to Make Regulatory Waves

Patient-Reported Outcomes in Oncology Expected to Make Regulatory Waves

Patient-reported outcomes, or PROs, are going to play a larger role in FDA cancer drug approvals, according to an expert in the field.

General Oncology

Identifying the Needs of Multidisciplinary Team Treating Geriatics Cancer Patients

The objective of this initiative was to identify gaps in oncology clinicians' knowledge, competence, and performance with respect to treatment of geriatric patients with cancer, whether in an academic medical center or community setting.

General Oncology Reducing the Reliance on Opioids for Cancer Pain: Is the Switch to Cannabis a Viable Option?

Reducing the Reliance on Opioids for Cancer Pain: Is the Switch to Cannabis a Viable Option?

Articles discussing the use of cannabis as a substitute for opioids highlight the limitations of the existing scientific evidence in the field.

General Oncology Cancer Death Rates Continue to Decline, but Socioeconomic Gaps Widen

Cancer Death Rates Continue to Decline, but Socioeconomic Gaps Widen

The continuous decline in cancer deaths over the past 25 years was attributed to improvements in screening, treatment.

General Oncology Should Widespread Early Detection Cancer Screening End?

Should Widespread Early Detection Cancer Screening End?

Experts examined the role of population-based early detection cancer screening.

General Oncology Checkpoint Inhibitors Boost Cancer Vaccine Research

Checkpoint Inhibitors Boost Cancer Vaccine Research

Researchers are excited about the prospect to use vaccines in combination with checkpoint inhibitors to improve the body's cancer-fighting ability.

Skin Cancer A Common Factor Links Mechanisms of Acquired Resistance to Melanoma Treatment

A Common Factor Links Mechanisms of Acquired Resistance to Melanoma Treatment

Inhibition of ER translocation prevented both ERK reactivation and autophagy, suggesting a potential strategy for improving BRAF and MEK inhibition therapy outcomes.

General Oncology A Closer Look at Reporting Toxicities in Cancer Clinical Trials

A Closer Look at Reporting Toxicities in Cancer Clinical Trials

QoL for patients with cancer is reduced just as much by the accumulation of low-level toxicities as it is from high-level adverse events.

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