Cyramza Gains New Indication for Metastatic Lung Cancer (NSCLC)

Share this content:
The FDA has expanded the indication of Cyramza for the treatment of metastatic NSCLC.
The FDA has expanded the indication of Cyramza for the treatment of metastatic NSCLC.

The Food and Drug Administration (FDA) has expanded the indication of Cyramza (ramucirumab; Eli Lilly) for the treatment of patients with metastatic non-small cell lung cancer (NSCLC).

Its expanded approval for treatment of metastatic NSCLC in combination with docetaxel is based on a clinical trial of patients with previously treated and progressive lung cancer (n=1,253).

Patients were randomized to Cyramza plus docetaxel or a placebo plus docetaxel. Study results showed that half of the patients treated with Cyramza plus docetaxel survived an average of 10.5 months vs. 9.1 months for half of the patients in the placebo plus docetaxel group.

RELATED: Rociletinib May Be Safe, Effective for the Treatment of EGFR-Mutated Non-Small Cell Lung Cancer

Cyramza, a human IgG1 monoclonal antibody, is already indicated for treatment of advanced or metastatic, gastric, or gastro-esophageal junction adenocarcinoma with disease progression on or after prior fluoropyrimidine- or platinum-containing chemotherapy.

For more information call (800) 545-5979 or visit

Related Resources

You must be a registered member of Cancer Therapy Advisor to post a comment.

Sign Up for Free e-newsletters

Regimen and Drug Listings


Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Prostate Cancer Regimens Drugs
Rare Cancers Regimens
Renal Cell Carcinoma Regimens Drugs
Skin Cancer Regimens Drugs
Urologic Cancers Regimens Drugs