Repeat Prostate Biopsies Raise Infection Risk

Share this content:
Repeat Prostate Biopsies Raise Infection Risk
Repeat Prostate Biopsies Raise Infection Risk

(HealthDay News) — For men with prostate cancer who are under active surveillance, repeated biopsies are associated with increased risk of infectious complications, according to research published in the March issue of The Journal of Urology.

Behfar Ehdaie, MD, of the Memorial Sloan-Kettering Cancer Center in New York City, and colleagues prospectively analyzed data for 591 consecutive patients who underwent prostate biopsy. The researchers sought to assess the risk of infectious complications associated with repeat biopsies in active surveillance for prostate cancer.

The researchers found that 14 patients (3.5%) had infectious complications (some resulting in hospitalization) from prostate biopsy. Urine cultures were positive in five patients; fluoroquinolone-resistant isolates were detected in four patients, including two patients with extended spectrum beta-lactamase producing isolates.

RELATED: Male Reproductive Cancers Resource Center

The number of previous prostate biopsies was significantly associated with increased risk of infectious complications (odds ratio, 1.33; 95% confidence interval, 1.01 to 1.74).

"The management of men with low-risk prostate cancer on active surveillance requires serial repeat biopsies, which exposes these men to infectious complications with each biopsy," the researchers wrote. "Men with prostate cancer on active surveillance should be informed of the risks associated with serial repeat prostate biopsies."

One researcher disclosed financial ties to Steba Biotech.


  1. Ehdaie B, Vertosick E, Spaliviero M, et al. The Impact of Repeat Biopsies on Infectious Complications in Men with Prostate Cancer on Active Surveillance. J Urol. 2014; 191(3):660-664.

Related Resources

You must be a registered member of Cancer Therapy Advisor to post a comment.

Sign Up for Free e-newsletters

Regimen and Drug Listings


Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Prostate Cancer Regimens Drugs
Rare Cancers Regimens
Renal Cell Carcinoma Regimens Drugs
Skin Cancer Regimens Drugs
Urologic Cancers Regimens Drugs