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Cachexia Index in Advanced Non-Small-Cell Lung Cancer Patients

Cachexia Index in Advanced Non-Small-Cell Lung Cancer Patients

[Clinical Medicine Insights: Oncology] Cancer cachexia affects many advanced non-small-cell lung cancer (NSCLC) patients.

Validation study of the modified injection technique for internal mammary sentinel lymph node biopsy in breast cancer

Validation study of the modified injection technique for internal mammary sentinel lymph node biopsy in breast cancer

[OncoTargets and Therapy] According to the hypothesis of internal mammary sentinel lymph node, lymphatic drainage pattern, a modified radiotracer injection technique was established.

Gemcitabine-Induced Pulmonary Toxicity: A Case Report of Pulmonary Veno-Occlusive Disease

Gemcitabine-Induced Pulmonary Toxicity: A Case Report of Pulmonary Veno-Occlusive Disease

[Clinical Medicine Insights: Oncology] Although myelosuppression is the most adverse event of this therapy, gemcitabine might induce severe pulmonary toxicities.

Imatinib in the treatment of chronic myeloid leukemia: current perspectives on optimal dose

Imatinib in the treatment of chronic myeloid leukemia: current perspectives on optimal dose

[Blood and Lymphatic Cancer Targets and Therapy] Imatinib was the first tyrosine kinase inhibitor (TKI), successfully used in a clinical setting.

Non-Hodgkin Lymphoma of the Stomach in a Patient Treated With Natalizumab

Non-Hodgkin Lymphoma of the Stomach in a Patient Treated With Natalizumab

[Clinical Medicine Insights: Oncology] Given the absence of association between multiple sclerosis, diffuse large B-cell lymphoma, causal association with natalizumab cannot be excluded.

Biomarkers in Hematological Malignancies: A Review of Molecular Testing in Hematopathology

Biomarkers in Hematological Malignancies: A Review of Molecular Testing in Hematopathology

[Cancer Control] Molecular testing is entrenched in the workup and management of hematological malignancies.

BRAF mutations in non-small cell lung cancer

BRAF mutations in non-small cell lung cancer

[Translational Lung Cancer Research] This research investigates the prevalence and clinicopathological features of BRAF mutations in non-small cell lung cancer (NSCLC) cases submitted for routine mutation testing.

CD151—A Striking Marker for Cancer Therapy

CD151—A Striking Marker for Cancer Therapy

[Biomarkers in Cancer] Cluster of differentiation 151 (CD151) functions at various stages of cancer, including metastatic cascade and primary tumor growth, reinforcing the importance of CD151 as a target in oncology.

Role of the WASP and WAVE family proteins in breast cancer invasion and metastasis

Role of the WASP and WAVE family proteins in breast cancer invasion and metastasis

[Breast Cancer: Targets and Therapy] This review focuses on the role of the WASP/WAVE family in breast cancer cell invasion and migration.

Threading the cloak: palliative care education for care providers of adolescents, young adults with cancer

Threading the cloak: palliative care education for care providers of adolescents, young adults with cancer

[Clinical Oncology in Adolescents and Young Adults] Integration of palliative care at the time of diagnosis enables a supportive partnership with the medical team.

Internalization: Acute apoptosis of breast cancer cells using herceptin-immobilized gold nanoparticles

Internalization: Acute apoptosis of breast cancer cells using herceptin-immobilized gold nanoparticles

[Breast Cancer: Targets and Therapy] Gold nanoparticles (GNPs) can be used in the imaging of tumors, as delivery agents for antitumor drugs, and for nonaggressive amputation treatments.

Platelet Transfusion for Patients with Cancer

Platelet Transfusion for Patients with Cancer

[Cancer Control] Platelet transfusion can often be a vital aspect aspect of managing cancer, as treatment courses can weaken the function of the cells requires to stop bleeding.

An Interesting Pathological Diagnosis: Adenoid Cystic Carcinoma in an Adolescent Girl

An Interesting Pathological Diagnosis: Adenoid Cystic Carcinoma in an Adolescent Girl

[Breast Cancer: Basic and Clinical Research] This case study examines a rare occurrence of adenoid cystic carcinoma (ACC) in a 19-year-old woman.

Intraperitoneal Follicular Dendritic Cell Sarcoma: Role of Chemotherapy and Bone Marrow Allotransplantation in Locally Advanced Disease?

Intraperitoneal Follicular Dendritic Cell Sarcoma: Role of Chemotherapy and Bone Marrow Allotransplantation in Locally Advanced Disease?

[Clinical Medicine Insights: Oncology] Intraperitoneal location of follicular dendritic cell sarcoma (FDCS) is very uncommon and is associated with a particularly aggressive clinical course.

Evaluating the safety and efficacy of axitinib in the treatment of advanced renal cell carcinoma

Evaluating the safety and efficacy of axitinib in the treatment of advanced renal cell carcinoma

[Cancer Management and Research] Axitinib is approved for use in the second-line setting for patients with metastatic renal cell carcinoma.

Intraoperative radiotherapy in the treatment of gastrointestinal malignancies

Intraoperative radiotherapy in the treatment of gastrointestinal malignancies

[Translational Cancer Research] Intraoperative radiotherapy (IORT) has emerged as a technique to deliver a single high dose of radiation to a target volume at the time of an operation.

Current and Emerging Therapies for Bone Metastatic Castration-Resistant Prostate Cancer

Current and Emerging Therapies for Bone Metastatic Castration-Resistant Prostate Cancer

[Cancer Control] New developments in metastatic castration-resistant prostate cancer (mCRPC) have resulted in several new therapies.

Multiple myeloma: Optimal management and long-term disease control

Multiple myeloma: Optimal management and long-term disease control

[Blood and Lymphatic Cancer: Targets and Therapy] Myeloma displays considerable heterogeneity and, over time, control of disease can be lost. New strategies to combat myeloma incorporate risk stratification to provide more individualized therapy.

The Use of Pharmacogenomics for Selection of Therapy in Non-Small-Cell Lung Cancer

The Use of Pharmacogenomics for Selection of Therapy in Non-Small-Cell Lung Cancer

[Clinical Medicine Insights: Oncology] Performance status is the only known clinical predictor of outcome in patients with advanced non-small-cell lung cancer (NSCLC), but pharmacogenomic markers may also correlate with outcome. This study attempts to correlate clinical and pharmacogenomic measures with overall survival.

Incidence and prognostic impact of high-risk HPV tumor infection in cervical esophageal carcinoma

Incidence and prognostic impact of high-risk HPV tumor infection in cervical esophageal carcinoma

[Journal of Gastrointestinal Oncology] This study examines outcomes of CEC patients treated with CRT and the incidence and potential role of HPV tumor infection in CEC lesions.

Targeted treatment of mutated <i>EGFR</i>-expressing non-small-cell lung cancer: focus on erlotinib with companion diagnostics

Targeted treatment of mutated EGFR-expressing non-small-cell lung cancer: focus on erlotinib with companion diagnostics

[Lung Cancer: Targets and Therapy] The appropriate role of EGFR mutation analysis in the treatment of patients with NSCLC is constantly evolving; EGFR mutation testing can help simplify the drug discovery process and individualize cancer therapy.

Diagnosis and Management of Castleman Disease

Diagnosis and Management of Castleman Disease

[Cancer Control] Castleman disease is a lesser seen lymphoproliferative disorder, which is characterized as either localized or multicentric, with differing treatments typically utilized for each type.

Mining Cancer-Specific Disease Comorbidities from a Large Observational Health Database

Mining Cancer-Specific Disease Comorbidities from a Large Observational Health Database

[Cancer Informatics] When examined, cancer comorbidities can reveal valuable clues to understanding the underlying genetic mechanisms of cancers. The comorbidity patterns among different patient groups and the effect of age and gender on cancer comorbidity patterns are investigated.

Treating Advanced Melanoma: Current Insights and Opportunities

Treating Advanced Melanoma: Current Insights and Opportunities

[Cancer Management and Research] Although thin melanomas have an excellent prognosis after sufficient surgical treatment, melanoma disease in advanced stages still proves to be a therapeutic challenge.

Human Papilloma Virus and Squamous Cell Carcinoma of the Anus

Human Papilloma Virus and Squamous Cell Carcinoma of the Anus

[Clin Med Insights Oncol] HPV is a risk factor for anal intraepithelial neoplasia (AIN). Etiology, anatomy, pathogenesis, management of squamous cell carcinoma (SCC) discussed.

Current Approaches and Emerging Directions in HER2-resistant Breast Cancer

Current Approaches and Emerging Directions in HER2-resistant Breast Cancer

[Breast Cancer (Auckl)] Human epidermal growth factor receptor-2 is overexpressed in up to 30% of breast cancers; indicative of poor prognosis.

PD-1 Pathway Inhibitors: Changing the Landscape of Cancer Immunotherapy

PD-1 Pathway Inhibitors: Changing the Landscape of Cancer Immunotherapy

[Cancer Control] Immunotherapeutic approaches to treating cancer have been evaluated during the last few decades with limited success.

Biomarkers of HIV-associated Cancer

Biomarkers of HIV-associated Cancer

[Biomark Cancer] Biomarkers can provide great opportunities in the management of the most common HIV-associated malignancies, namely, Kaposi sarcoma, non-Hodgkin's lymphoma, and invasive cervical cancer.

FDG-PET/CT in the Assessment of Treatment Response after Oncologic Treatment of Head and Neck Squamous Cell Carcinoma

FDG-PET/CT in the Assessment of Treatment Response after Oncologic Treatment of Head and Neck Squamous Cell Carcinoma

[Clin Med Insights Ear Nose Throat] FDG-PET/CT is used to monitor treatment response after definitive (chemo)radiotherapy for head and neck squamous cell carcinoma, but its usefulness remains controversial.

New Therapies in T-cell Lymphoma

New Therapies in T-cell Lymphoma

[Lymphoma and Chronic Lymphocytic Leukemias] Biomarker-driven chemotherapeutics is becoming a critical part of the state-of-the-art treatment in clinical trials involving patients with T-cell lymphoma.

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