SABCS 2013

Molecular Subtyping Bests Standard in Predicting Breast Cancer Outcomes

Molecular Subtyping Bests Standard in Predicting Breast Cancer Outcomes

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Molecular tumor subtyping offers more accurate prediction of long-term breast cancer outcomes.

Neoadjuvant Veliparib Plus Carboplatin Holds Promise for TNBC

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Adaptive randomization study finds neoadjuvant veliparib plus carboplatin may improve pCR in TNBC.

Switching Chemo Regimen After Cycle 1 Not Beneficial in Metastatic Breast Cancer

Switching Chemo Regimen After Cycle 1 Not Beneficial in Metastatic Breast Cancer

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Patients with metastatic breast cancer did not benefit from switching to a second-line chemotherapy regimen after one cycle of first-line therapy.

Ramucirumab Does Not Improve Survival in Advanced Breast Cancer

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Adding ramucirumab to docetaxel does not improve survival among patients with HER2-negative, advanced breast cancer.

Neoadjuvant Carboplatin, Bevacizumab Improve pCR Rates in TNBC

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Adding carboplatin or bevacizumab to standard chemotherapy improves pCR in TNBC.

Bisphosphonate Not Beneficial for Chemoresistant Breast Cancer

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Zoledronate does not improve survival rates among women with chemoresistant breast cancer.

Locoregional Treatment After Chemo Not Recommended for Metastatic Breast Cancer

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Women with metastatic breast cancer who respond to chemotherapy should not receive locoregional treatment.

Benefits of Mammography Screening Consistent Across Studies

Benefits of Mammography Screening Consistent Across Studies

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Reviews show a substantial reduction in breast cancer mortality with screening.

PIK3CA Mutations Implicated in Treatment-Resistance for Some Breast Cancers

PIK3CA Mutations Implicated in Treatment-Resistance for Some Breast Cancers

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Some breast tumors resistance to chemotherapy and HER2-targeted therapy is associated with PIK3CA mutations.

Combo Dasatinib/Letrozole Delays Disease Progression in Some Breast Cancers

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Dasatinib plus letrozole delays disease progression in some advanced breast cancers.

Exercise Eases AI-Associated Joint Pain

Exercise Eases AI-Associated Joint Pain

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Postmenopausal breast cancer survivors experienced improvement in AI-associated joint pain with physical exercise.

Anastrozole Chemoprevention Halves Breast Cancer Risk

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Anastrozole decreased risk for breast cancer in postmenopausal women.

Tumor-Infiltrating Lymphocytes Predict Trastuzumab Response

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Higher levels of tumor-infiltrating lymphocytes are linked to increased clinical benefit to trastuzumab plus chemotherapy in HER2-positive breast cancer.

Skipping Postop Radiotherapy OK for Some with Breast Cancer

Skipping Postop Radiotherapy OK for Some with Breast Cancer

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Some older women with breast cancer receiving hormone therapy can omit postoperative radiotherapy.

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