PHQ-2 Questionnaire Effective in Screening for Mood Disorders Among Patients With Cancer

Share this content:
In screening for mood disorders among patients with cancer, the PHQ-2 diagnostic tool demonstrates effective psychometric properties.
In screening for mood disorders among patients with cancer, the PHQ-2 diagnostic tool demonstrates effective psychometric properties.

In screening for mood disorders among patients with cancer, the 2-item Patient Health Questionnaire (PHQ-2) diagnostic tool demonstrates effective psychometric properties, according to a study published in Cancer.1

Researchers evaluated 455 patients who underwent the 9-item Patient Health Questionnaire (PHQ-9), the National Comprehensive Cancer Network Distress Thermometer (NCCN-DT), the 25-item Hopkins Symptom Checklist (HSCL), and the PHQ-2.

Forty-five percent of patients had breast cancer, 11% had gastrointestinal cancer, 10% had lung cancer, 6% had gynecologic cancer, and 27% had another form of cancer.

Forty-two patients who exceeded screening cutoffs and 37 patients who had a negative screening underwent the Structured Clinical Interview for DSM-IV (SCID) mood disorder modules over the telephone. Among these observed patients, 8 were considered to have major depression, 2 had dysthymia, and 6 had an adjustment disorder.

RELATED: Possible Link Between Spousal Depressed Mood, Cancer Survivor Quality of Life

The PHQ-2 diagnostic tool demonstrated good psychometric properties in mood disorder screening for those patients with a cutoff of at least 3. The cutoff for the PHQ-9 was greater than 9, and the NCCN-DT did not detect depression.

Reference

  1. Wagner LI, Pugh SL, Small Jr W, et al. Screening for depression in cancer patients receiving radiotherapy: Feasibility and identification of effective tools in the NRG Oncology RTOG 0841 trial. Cancer. 2016 Nov 10. doi: 10.1002/cncr.29969 [Epub ahead of print]

Related Resources

You must be a registered member of Cancer Therapy Advisor to post a comment.

Sign Up for Free e-newsletters

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Prostate Cancer Regimens Drugs
Rare Cancers Regimens
Renal Cell Carcinoma Regimens Drugs
Skin Cancer Regimens Drugs
Urologic Cancers Regimens Drugs