Among Caucasians, Males More Likely to Die of Melanoma Than Females

This article originally appeared here.
Share this content:
Melanoma Mortality Higher for Males Than Females
Melanoma Mortality Higher for Males Than Females

(HealthDay News) -- White males with melanoma are more likely to die from the disease compared with white females with melanoma, according to a study published online June 26 in JAMA Dermatology.

Christina S. Gamba, M.D., from Stanford University in Palo Alto, Calif., and colleagues examined survival in 26,107 non-Hispanic white adolescents and young adults diagnosed with primary invasive melanoma of the skin (at 15 to 39 years of age) from 1989 to 2009.

After a mean follow-up of 7.5 years, the researchers identified 1,561 melanoma-specific deaths. Although males represented only 39.8% of melanoma cases, they comprised 63.6% of melanoma-specific deaths. After adjusting for factors such as histologic subtype, males were significantly more likely to die of melanoma compared with age-matched females (hazard ratio, 1.55). 

Males were more likely to die regardless of age group, and even males with thin melanomas were significantly more likely to die compared with age-matched females (hazard ratio, 1.95). Adjusting for health insurance and socioeconomic status had no significant effect.

"Male sex is associated with worse survival among white adolescents and young adults with melanoma after controlling for thickness and other prognostic factors," Gamba and colleagues conclude. "Further investigation of possible biological mechanisms that account for these sex differences is merited."

Related Resources

You must be a registered member of Cancer Therapy Advisor to post a comment.

Sign Up for Free e-newsletters

Regimen and Drug Listings


Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Prostate Cancer Regimens Drugs
Rare Cancers Regimens
Renal Cell Carcinoma Regimens Drugs
Skin Cancer Regimens Drugs
Urologic Cancers Regimens Drugs