Bladder Cancer Prognosis Modified By Genetic Variants
Variants impact time to first recurrence, survival for patients with urothelial-cell carcinoma.
Diagnosis & Disease Information
Expert: Bladder Cancer Study Validates Personalized Medicine Concept
Gopal N. Gupta, MD, discusses the findings of a study on bladder cancer mutations and response to everolimus.
Bladder Tumor Mutations May ID Responders to Everolimus
Genomic profiling of the tumor of a patient who had an exceptional response to everolimus may lead to a personalized approach to bladder cancer.
Pre-existing Screening, Therapies May Benefit Bladder Cancer Patients
HER2 screening and emetine dihydrochloride may offer patients with bladder cancer more effective treatment options.
Metformin Fails to Decrease Bladder Cancer Risk
Metformin doesn’t significantly reduce risk of bladder cancer in patients with type 2 diabetes.
Trimodal Therapy Effective in Invasive Bladder Urothelial Carcinoma Not Suitable for Cystectomy
Trimodal therapy is “appropriate” after transurethral surgery in muscle-invasive bladder urothelial carcinoma not suitable for cystectomy.
Partial, Complete Responses to Bladder-preserving Therapy Yield Similar Outcomes
Partial and complete responders to bladder-preserving induction chemotherapy for bladder cancer have similar long-term outcomes.
Poor Accrual Primary Reason Clinical Trials Fail to Complete
Of the 7,776 adult cancer clinical trials initiated in 2005, approximately 20% failed to complete enrollment for reasons other than toxicity or efficacy of intervention.
IBCG Calls for New Definition in Bladder Cancer
Group proposes standard definition of progression in nonmuscle invasive bladder cancer.
Mortality Risk High among Current Smokers with Cancer
Current smokers at diagnosis who continue smoking have increased hazard ratios for various cancers
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