No PFS Benefit With Carotuximab in Advanced Angiosarcoma
Researchers compared carotuximab plus pazopanib with pazopanib alone in patients with advanced angiosarcoma.
Diagnosis & Disease Information
Patients With Axial Osteosarcoma May Have Higher Risk for Local Recurrence
Patient age and tumor site were linked to the risk of local recurrence, and histological response to neoadjuvant chemotherapy was tied to the risk of new metastatic disease.
Irinotecan-Temozolomide “Effective and Safe” for Relapsed Ewing Sarcoma
In a pooled analysis of 6 studies, 44% of patients responded to combination irinotecan and temozolomide.
Phthalates in Medications May Increase Risk of Childhood Cancers
Children prescribed a medication containing a phthalate had a 19% higher risk of developing any childhood cancer.
Osteosarcoma Incidence Highest in Black Patients
Black individuals had the highest incidence of osteosarcoma, but the worst survival was seen in American Indian/Alaska Native individuals.
Denosumab May Increase Risk of Local Recurrence in Giant Cell Tumor of the Bone
Researchers compared patients with giant cell tumor of the bone who were treated with surgery alone or surgery plus preoperative denosumab.
Bone Cancer Survivors Are at Increased Risk of Neurocognitive Difficulties
Researchers sought to measure the risk of long-term neurocognitive outcomes in survivors of osteosarcoma and Ewing sarcoma.
Tool Predicts Cancer-Specific Survival in Primary Long Bone Osteosarcoma
Researchers describe the development and validation of a risk-stratification system that uses clinicopathologic factors not included in a traditional TNM staging system.
No Benefit Seen With Longer Antibiotic Course After Surgery for Bone Tumors
There were no significant differences between the treatment groups in rates of surgical site infections, unplanned operations, oncologic events, or all-cause mortality.
Most NCCN Radiotherapy Recommendations Not Backed by High-Level Evidence
Less than 10% of radiotherapy recommendations in 2020 NCCN guidelines were category 1 recommendations.
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