Q&A With Mark B. Gerstein, PhD, on Diagnostic Genomic vs Exomic Sequencing
“People have shown that the variant-identification quality of WGS is superior to WES,” said Dr Gerstein.
Bone Cancer
Patient-Reported Outcomes in Oncology Expected to Make Regulatory Waves
Patient-reported outcomes, or PROs, are going to play a larger role in FDA cancer drug approvals, according to an expert in the field.
Reducing the Reliance on Opioids for Cancer Pain: Is the Switch to Cannabis a Viable Option?
Articles discussing the use of cannabis as a substitute for opioids highlight the limitations of the existing scientific evidence in the field.
Cancer Death Rates Continue to Decline, but Socioeconomic Gaps Widen
The continuous decline in cancer deaths over the past 25 years was attributed to improvements in screening, treatment.
Should Widespread Early Detection Cancer Screening End?
Experts examined the role of population-based early detection cancer screening.
Checkpoint Inhibitors Boost Cancer Vaccine Research
Researchers are excited about the prospect to use vaccines in combination with checkpoint inhibitors to improve the body’s cancer-fighting ability.
Is Real-World Evidence a Complement to Randomized Clinical Trials?
Use of real-world data has the potential to accelerate drug and device approvals in rare diseases and advance precision medicine initiatives.
Gene-Delivery Method Generates Immune Checkpoint Antibodies In Vivo
In mice, DNA-encoded plasmids generated sufficient in vivo expression of immune checkpoint antibody CTLA-4; DMabs may one day rival traditional mAbs.
Preexisting Immunity to CRISPR-Cas9: A Problem for Gene Editing in Cancer?
Evidence is building to show that most people have preexisting immunity to CRISPR-based therapies. In cancer, however, it’s unclear how much that matters.
Cancer Recurrence: Tackling a Valid Survivor Fear
Researchers are learning that roughly half of survivors live with a moderate to high degree
of fear of recurrence, and teaching techniques to better cope with uncertainty is one way to
help.
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