Sex is Independent Predictor of Death in Patients With CNS Cancer
Young men had a higher risk of death after any brain tumor diagnosis.
Brain Cancer
Risk of Leptomeningeal Metastasis in Melanoma Linked to Anatomic, Surgical Factors
Researchers found that entry into the ventricle space during surgical resection elevated the risk of leptomeningeal disease in patients with melanoma brain metastases.
Maternal Hormonal Contraception, CNS Tumors Not Linked in Children
No significant association was seen between maternal hormonal contraception use and CNS tumors in children younger than 20 years.
HLA Variant May Predict Poor Outcomes of Immunotherapy in Cancer Patients
HLA-A*03 was associated with worse progression-free and overall survival.
Armodafinil Does Not Reduce Cancer-Related Fatigue in High-Grade Glioma
The proportion of patients who reported improvements in fatigue was similar across the treatment arms.
Dabrafenib Plus Trametinib Yields Responses in BRAF-Mutant Gliomas
Patients with low-grade and high-grade glioma achieved responses.
ONC201 Shows Clinical Efficacy in H3 K27M-Mutated Diffuse Midline Glioma
Among patients with a performance status of less than 80, 20.6% had an improvement in this metric.
Adding Nivolumab to Standard Care Does Not Improve Survival in Glioblastoma
The median PFS was 10.6 months in the nivolumab group and 10.3 months in the placebo group.
Neuro-Oncology Patient Satisfaction Maintained During COVID-19 Pandemic
Patient satisfaction scores before the pandemic were comparable to scores during the pandemic.
One-Third of Patients May Not Recover From TMZ-Induced Aplastic Anemia
Patients without hematologic recovery had an increased risk of febrile neutropenia, infection, hospitalization, and death.
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