Bevacizumab Adoption Tied to Use by Peers
The decision to adopt bevacizumab could be appraised by the prior level of uptake among their peers in their medical community.
Breast Cancer
Lack of Insurance Tied to Later Stage of Breast Cancer at Diagnosis
Almost half of higher stage of disease at diagnosis in racial/ethnic minorities explained by insurance status.
Notification Laws May Not Increase Knowledge of Dense Breast Risks
Women with lower education may be less likely to gain awareness of breast density due to the laws.
The FDA Approval Process Needs Refinement, Not a Total Overhaul
Even though overall drug development times have not changed, questions about the clinical benefit of the drugs that have been approved through expedited pathways are being raised.
No Link Found Between Hepatitis C Infection and Extrahepatic Cancers
A study of an Asian population failed to find a link between the virus and malignancies outside of the liver.
How Durable Are Responses to Targeted Therapies Across Single-Arm Cancer Trials?
Drugs approved based on changes to surrogate biomarker levels may be subject to measurement bias, according to investigators.
Cardiac Resynchronization Therapy Associated With Substantial Increase in LVEF in Patients With Chemotherapy-Induced Cardiomyopathy
Cardio-oncology is an emerging field focusing on the detection, monitoring, and treatment of cardiac dysfunction related to systemic or radiation therapy.
Reporting Mechanisms for Conflict of Interest Disclosures in Medicine Need Standardization
ASCO officials examined the discrepancies in financial disclosures across platforms and call for a simplified system.
Adding Trastuzumab to Chemotherapy Yields No Benefit for HER2-Low Disease
The addition of trastuzumab to adjuvant chemotherapy did not improve outcomes for patients with HER2-low invasive breast cancer, a phase 3 randomized trial showed.
PALB2 Linked to Increased Risk for Breast, Ovarian, and Pancreatic Cancer
Germline PALB2 pathogenic variants were associated with an increased risk of female or male breast cancer, as well as ovarian and pancreatic cancer.
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