2008 to 2017 Saw Drop in Malignant Brain Tumor Incidence
Incidence rates decreased overall but increased among children and adolescents.
CNS Cancers
Medicinal Cannabis Improves Quality of Life for Patients With High-Grade Gliomas
A 1:1 ratio of THC to CBD proved superior to a 4:1 ratio.
Carboplatin Intensification Beneficial for Group 3 Medulloblastoma
Therapy intensification with carboplatin improved five-year event-free survival in children with high-risk group 3 medulloblastoma only.
Very Elderly Can Benefit From Brain Tumor Surgery
While there is short-term excess mortality, cumulative survival is similar to the general population.
Adding Marizomib to Standard Care Did Not Improve Survival in Newly Diagnosed Glioblastoma
There was no improvement in progression-free or overall survival with marizomib.
Early Radiotherapy Preserves Vision in Certain Children With Glioma
Early radiotherapy may preserve visual acuity for certain children with sporadic optic pathway/hypothalamic gliomas.
Global Variation Found in Histology Distribution of Brain Tumors
The proportion of childhood medulloblastomas varied widely between countries, offsetting the low proportion of low-grade astrocytomas in several countries.
FDA Grants Orphan Drug Status to Berubicin for Malignant Gliomas
he designation is supported by data from a phase 1 trial conducted by Reata Pharmaceuticals in 2016. Findings from the study showed 44% of patients treated with berubicin (n=11 out of 25) experienced a statistically significant improvement in progression free survival.
Short Treatment Delays May Not Hamper Survival in Glioblastoma
For patients with glioblastoma, short delays in the initiation of chemoradiotherapy after surgery were not linked to worse survival — yet initiation too soon was.
Pediatric Brain Cancer Outcomes Worse for Black, Hispanic Patients
Disparities for disease severity not seen at diagnosis, meaning postdiagnosis factors may affect outcome.
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