Neoadjuvant Chemo Appears No Better Than Upfront Surgery for Colon Cancer
Neoadjuvant chemotherapy does not improve survival outcomes vs upfront surgery in patients with locally advanced colon cancer, a phase 3 trial suggests.
Neoadjuvant chemotherapy does not improve survival outcomes vs upfront surgery in patients with locally advanced colon cancer, a phase 3 trial suggests.
Adding HIPEC and mitomycin C to surgical resection improves locoregional control in patients with locally advanced colon cancer, a study suggests.
Postoperative physical activity is associated with improved outcomes in patients with stage III colon cancer, a study suggests.
Studies suggest that ctDNA testing has prognostic value in colorectal cancer, but more research is needed before it can be used in practice.
Elevated levels of inflammatory biomarkers are associated with worse outcomes for patients with stage III colon cancer, a study suggests.
Six weeks of neoadjuvant chemotherapy was associated with a higher rate of complete resection and a lower rate of disease recurrence.
Exercise during chemotherapy may preserve cardiorespiratory fitness, a study suggests.
Neoadjuvant nivolumab and ipilimumab produced an “unprecedented” major pathologic response rate in the NICHE-2 study, according to the lead study author.
Immune checkpoint inhibitor therapy appears to maintain or improve quality of life in patients with solid tumor malignancies.
Overall, adjuvant chemotherapy does not appear to increase the risk of second cancers for patients with stage III-IV colon cancer.