Colorectal Cancer Archives - Cancer Therapy Advisor

High adherence to the at-home, stool-based screening test is a positive sign, but its impact on survival outcomes is still unclear.

ASCO 2021

Final Results Support Pembrolizumab as Standard of Care in MSI-H/dMMR Metastatic Colorectal Cancer

By

Sucharita Mistry, PhD

June 14, 2021

Pembrolizumab improved progression-free survival but not overall survival.

Scoring system may identify patients who do not need colonoscopy to screen for colorectal cancer (CR

ASCO 2021

Capecitabine Maintenance Improves Progression-Free Survival in Metastatic Colorectal Cancer

By

Sucharita Mistry, PhD

June 10, 2021

There was no improvement in overall survival.

Lymph node with metastatic colonic adenocarcinoma

ASCO 2021

Panitumumab Plus 5FU/LV: ‘Preferred’ Maintenance Regimen in RAS Wild-Type Metastatic Colorectal Cancer

By

Sucharita Mistry, PhD

June 9, 2021

Adding panitumumab to 5-fluorouracil and leucovorin improved progression-free survival.

Processed meats, the likes of which include bacon, hot dogs and sausages, can cause cancer.

Gastrointestinal Cancers

Nongenetic Risk Factors for Colorectal Cancer May Differ by Disease Onset, Subsite

By

Sucharita Mistry, PhD

June 3, 2021

Some nongenetic risk factors for late-onset colorectal cancer may not be relevant for early-onset disease.

Gastrointestinal Cancers

Family History of Polyps Raises Colorectal Cancer Risk

By

Christina Bennett, MS

May 25, 2021

Having a first-degree relative with colorectal polyps may increase a person’s risk of developing colorectal cancer, indicating that earlier screening is warranted.

Colonic stenting can be used as a temporizing measure to help bridge the patient to surgery for opti

Gastrointestinal Cancers

Pembrolizumab May Improve Health-Related Quality of Life in Metastatic Colorectal Cancer

By

Christina Bennett, MS

May 25, 2021

Health-related quality of life tended to improve over time with pembrolizumab but not with chemotherapy.

Prostate Cancer Treatment May Increase Colorectal Cancer Risk

Gastrointestinal Cancers

Patients With Comorbidities Are More Likely to Undergo Colorectal Cancer Screening

By

Christina Bennett, MS

May 25, 2021

Patients without comorbidities were less likely to undergo screening for colorectal cancer than patients with comorbidities.

Gastrointestinal Cancers

Outcomes Remain Poor for Colorectal Cancer Patients with Brain Metastases

By

Jennifer Larson

May 4, 2021

A retrospective cohort study investigated the incidence of and risk factors for brain metastases in patients with colorectal cancer.

Some patients with rectal cancer who experience complete clinical response after neoadjuvant therapy

Gastrointestinal Cancers

Neoadjuvant Chemotherapy With FOLFIRINOX Followed by Chemoradiotherapy Significantly Prolongs Disease-Free Survival in Stage T3 or T4 Rectal Cancer

By

Colby Stong

April 29, 2021

The trial found that the combination improved outcomes in patients with locally advanced rectal cancer compared with standard chemoradiotherapy, surgery, and adjuvant chemotherapy.

A doctor explains a medication to an older patient.

Gastrointestinal Cancers

Chemotherapy Associated With Reduced Risk of Alzheimer Disease in CRC Survivors

By

Andrea S. Blevins Primeau, PhD, MBA

April 9, 2021

A retrospective study was conducted to identify the relationship between Alzheimer disease or other neurocognitive disorders and previous treatment with chemotherapy for colorectal cancer.