Study Launched to Assess Real-World Outcomes of At-Home CRC Screening
A large, prospective, observational study seeks to assess the real-world outcomes of people who use the at-home colorectal cancer screening test Cologuard.
Colorectal Cancer
Prediagnostic Colonoscopy Cuts Colorectal Cancer Death Risk
Mortality risk drops 17 percent with one colonoscopy before diagnosis, 45 percent with three colonoscopies.
Colorectal Liver Metastasis Linked to Chronic Hepatitis B Infection Status
A retrospective analysis of more than 7000 patients found a potential association between colorectal cancer, hepatic metastasis, and chronic HBV status.
High Concordance Rate for Solid and Liquid Biopsy-Based NGS Results Reported in Metastatic CRC
One finding was a drop in concordance rate for clonal alterations when NGS was performed on tumor tissue and ctDNA samples collected following treatment initiation.
Adherence to the World Cancer Research Fund Recommendations and Colorectal Cancer Risk: Examining the Link
Adherence to the 2018 WCRF/AICR recommendations as measured by a multicomponent “lifestyle score” was associated with a statistically significant decreased risk of CRC in men.
High-Intensity Surveillance of Colorectal Adenomas Modeled
Model shows high-intensity surveillance could provide modest, clinically relevant benefits at acceptable cost.
Patients, Caregivers Share High Level of Agreement in Assessments of Colorectal Cancer Care
Survey results show level of concordance between patients with CRC and their caregivers when rating care quality. The survey also measured whether clinical or demographic factors influenced the agreement between patient-caregiver pairs.
Risk of Cancer in Individuals With Lynch Syndrome Can Vary With Age, Gender, and MMR Gene Alteration
According to this prospective study, the lifetime risk of cancer in men with a pathogenic germline MSH6 alteration is relatively low.
Younger CRC Patients More Likely to Present With Abdominal Pain
Young colorectal cancer patients more often present via emergency; have lowest percentage early-stage cancer.
Metastatic Colorectal Cancer Treatment Options: New BRAF V600E Data
The combination of ENCO and BINI had greater antitumor activity against mCRC cells with the BRAF V600E mutation.
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