Colorectal Cancer Archives - Page 53 of 53 - Cancer Therapy Advisor

Colorectal Cancer

Bevacizumab Combo Improves Colorectal Cancer Survival

The addition of bevacizumab to combination chemotherapy for the treatment of stage IV colorectal cancer increases overall survival, particularly for patients receiving irinotecan-based chemotherapy regimens, but is associated with increased rates of strokes and gastrointestinal (GI) perforations, according to a study published online January 17 in the Journal of Clinical Oncology.

New Predictors of Treatment Response Identified for CRC

In colorectal cancer patients, hypermethylation of the gene encoding transcription factor AP-2 epsilon (TFAP2E), which targets a gene involved in chemoresistance (dickkopf homolog 4 protein [DKK4]), is associated with treatment resistance to fluorouracil but not irinotecan or oxaliplatin.

Next post in Uncategorized