Zandelisib Displays “Exemplary” Efficacy in Relapsed/Refractory Follicular Lymphoma
Zandelisib produced a high overall response rate in a phase 2 trial of patients with relapsed/refractory follicular lymphoma.
Zandelisib produced a high overall response rate in a phase 2 trial of patients with relapsed/refractory follicular lymphoma.
Tisagenlecleucel can produce responses in children and young adults with relapsed/refractory B-cell non-Hodgkin lymphoma, a phase 2 study suggests.
Obinutuzumab plus chemotherapy improved progression-free survival and time to next treatment.
Two treatment-related factors and the frequency of 6 cell types were associated with response to COVID-19 vaccination.
Extended decitabine produced a similar overall survival rate as standard chemotherapy, but decitabine had a better safety profile.
Axi-cel improved event-free survival vs standard care in older patients with relapsed/refractory large B-cell lymphoma.
Patients with previously untreated CLL had superior PFS with fixed duration venetoclax plus obinutuzumab, with or without ibrutinib.
Overall, there was no improvement in complete response or survival outcomes among patients who received bortezomib.
The overall response rate at cycle 4 was 61.5%, and none of these patients relapsed.
The 2 regimens produced similar efficacy outcomes, but adverse events were more common in the R-CODOX-M/R-IVAC arm.