There was a trend of different 5-year RFS among the groups, with the shortest among patients with MLH1-hypermethylated disease at 78.6% compared with 95.5% among patients with other causes of MMRd.
The study researchers reported that endometrial cancers with these somatic mutations have unfavorable pathologic features.
Researchers found that the benefit of adjuvant therapy differed depending on the status of peritoneal cytology in women with endometrial cancer.
Researchers sought to determine if LNG-IUD is effective and whether the addition of weight loss or metformin can further improve response in patients with EAC and EHA.
Investigators of the observational study sought to clarify the time-dependent effects between long-term oral contraceptive use and risk for breast, ovarian, and endometrial cancer risk.
The PD-1 inhibitor retifanlimab showed antitumor activity with a tolerable safety profile among patients with MSI-H/dMMR endometrial cancer.
Does abemaciclib and letrozole effective slow or stop endometrial cancer cell growth?
All patients will receive mirvetuximab soravtansine and pembrolizumab in this study.
A phase 3 study seeks to evaluate the value of selecting therapy based on molecular profiling.
Patients with advanced or recurrent endometrial cancer enrolled in the experimental arm will receive atezolizumab in combination with paclitaxel and carboplatin.
