Phase 3 Trial for Oncolytic Viral Therapy Pexa-Vec in Advanced Liver Cancer Terminated Early
Pexa-Vec, in combination with sorafenib, has failed an interim futility analysis, leading to the early termination of the trial.
Gastrointestinal Cancer
Physical Activity, Overall Survival Not Linked in Metastatic CRC
Nine or more MET hours per week tied to lower risk for grade ≥3 treatment-related adverse events.
Knowing the Appropriateness of Running Noninferiority Trials in Oncology
Researches took a critical look at noninferiority trials and determined that when a new intervention is “not worse,” the possibility exists that it is not better, either.
Patients, Caregivers Share High Level of Agreement in Assessments of Colorectal Cancer Care
Survey results show level of concordance between patients with CRC and their caregivers when rating care quality. The survey also measured whether clinical or demographic factors influenced the agreement between patient-caregiver pairs.
Tapping Into the Therapeutic Expertise of High-Volume Cancer Centers
Researchers examine how patient outcomes could be affected if patients were to receive systemic drug treatment at dedicated cancer centers versus at community health systems.
Risk of Cancer in Individuals With Lynch Syndrome Can Vary With Age, Gender, and MMR Gene Alteration
According to this prospective study, the lifetime risk of cancer in men with a pathogenic germline MSH6 alteration is relatively low.
Statins Linked to Lower Risk of Liver Cancer in Patients With Hepatitis B/C
Lipophilic statins were linked to a lower risk of hepatocellular carcinoma and death in a cohort of patients with chronic hepatitis B/C.
DAAs Cut Deaths in Those Treated for HCV-Related Liver Cancer
Findings seen for patients receiving direct-acting antivirals with complete response to liver cancer treatment.
New Trial Attempts to Make Genetic Counseling and Testing More Accessible
The researchers wrote that “genetic counseling must be further explored to find an optimal balance of clinical quality with increased access and financial sustainability.”
Aspirin May Improve Liver Function After Embolization of HCC
Study suggests aspirin is hepatoprotective, improves survival by reducing liver inflammation.
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