Waiting for CAR-T
Choosing the best bridging therapy for a patient, prior to administration of CAR-T, is dependent on the patient’s disease characteristics.
General Oncology
Use of Pathogenic BRCA1/2 Alterations as Pan-Cancer Biomarkers for Therapy Selection May Not be Appropriate
In this study, the degree of homologous recombination deficiency was not predictable across cancer types using BRCA1/2 status.
Proposed CMS Rule Change Would Restrict Access to Anticancer Medications
Of the 143 brand name protected class drugs that exist, more than half are antineoplastics.
Facilitating CAR-T Cell Therapy in Solid Tumors Through “Vaccine Boosting”
Bispecific CAR-T cells were engineered to target both tumor antigen and vaccine-specific antigens to boost CAR-T function through an amphiphilic vaccine.
State-Level Variation Noted in Economic Burden of Cancer
Lost earnings of $94.4 billion reported in the United States in 2015.
Cancer Drug Development: How Therapies Move Through the Pipeline
This fact sheet explains the processes involved in drug development and FDA drug approval.
Increased Cancer Risk Seen in Multiple Sclerosis Patients
Cancer risk up for MS patients versus non-MS controls, especially in respiratory, urinary, CNS organs.
Fluorouracil Injection Recalled Due to Glass Particulate
No reports of adverse events have been received at this time, as per the Company.
Fragmentation Pattern of Cell-Free DNA Can Reveal Cancer, Even at Early Stages
Machine learning algorithm detected 7 types of cancer in liquid biopsy and identified tissue of disease origin.
Solving the Obesity Paradox in Oncology
One potentially revolutionary hypothesis relates to the evolutionary processes involved in oncogenesis.
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