Temozolomide Prescribing Information Updated Under FDA’s Project Renewal Program
Temozolomide is the second drug to receive a labeling update under Project Renewal.
Diagnosis & Disease Information
Adding Ipilimumab to Nivolumab Doesn’t Provide Meaningful Benefit, Researchers Say
Adding ipilimumab to treatment with nivolumab does not provide a clinically meaningful benefit in patients with certain cancers, a meta-analysis suggests.
MRSI-Guided Dose Escalation of Radiotherapy Does Not Improve PFS, OS in Glioblastoma
Image-guided dose escalation of radiotherapy does not improve outcomes in patients with glioblastoma receiving concomitant temozolomide, a phase 3 trial suggests.
The Alien Inside My Brain: Case Study on Glioblastoma Multiforme
This case study outlines the workup and treatment of glioblastoma multiforme.
UCPVax Prompts Immune Responses in MGMT Unmethylated Glioblastoma
UCPVax, an anti-telomerase vaccine, has demonstrated immunogenicity in a phase 2 trial of patients with MGMT unmethylated glioblastoma.
Ultrasound Technique Delivers Paclitaxel Across Blood-Brain Barrier in Glioblastoma
An ultrasound technique allows for delivery of albumin-bound paclitaxel across the blood-brain barrier in patients with recurrent glioblastoma, a study suggests.
Adagrasib Shows Activity in Hard-to-Treat KRAS-Mutated Solid Tumors
Adagrasib produced responses in a phase 1/2 trial of patients with heavily pretreated, KRAS G12C-mutated solid tumors.
Artificial Intelligence Can Predict Cancer Survival Using Data From a Single Consultation
Artificial intelligence can predict survival in cancer patients using information from a patient’s initial consultation with an oncologist, a study suggests.
Investigational Therapy Gets Fast Track Status for Glioblastoma Multiforme
In mouse models, WP1122 outperformed temozolomide.
Convection-Enhanced Delivery of Topotecan Active in Glioblastoma
Chronic convection-enhanced delivery of topotecan was feasible and well tolerated in patients with recurrent glioblastoma.
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