Novel Genetic Variants Are Associated With Increased Risk of Cervical Cancer
Genetic variations in the PAX8, CLPTM1L, and HLA genes were found to be associated with a high risk of developing cervical cancer.
Gynecologic Cancers
Keytruda Plus Lenvima Gets Full Approval for Advanced Endometrial Cancer
The full approval was based on data from the confirmatory phase 3 KEYNOTE-775 trial.
Removing a Large Uterus via Minimally Invasive Surgery Linked to Local Recurrence of High-Grade Endometrial Cancer
The results raise concern about potential local tumor spill, according to researchers.
Unmet Social Needs, Distress Linked in Gynecologic Oncology Patients
Social isolation and lack of safety at home associated with distress; unmet needs also linked to treatment interruption.
Avelumab Doesn’t Improve Survival in Platinum-Refractory Ovarian Cancer
There was no improvement in progression-free or overall survival.
Two Doses of COVID-19 Vaccine Appear Necessary to Protect Cancer Patients on Active Treatment
Cancer patients had a low rate of seropositivity after the first vaccine dose but not after the second dose.
Oral Contraceptives Lower Ovarian Cancer Risk in BRCA Carriers
Findings seen in BRCA1 and BRCA2 mutation carriers; reduction greater with longer duration of use in BRCA1 carriers.
Women’s Cancer Screenings Plummeted During Pandemic
Decline especially noticeable among women of racial and ethnic minority groups with low incomes.
Rucaparib Bests Standard of Care in BRCA-Mutated, Relapsed Ovarian Cancer
Rucaparib prolonged progression-free survival.
Benefit of Niraparib Maintenance May Extend Beyond First Progression in Ovarian Cancer
There was an improvement in second progression-free survival, but not overall survival, with niraparib.
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