Hematopoietic Stem Cell Transplantation Archives

Consolidative Stem Cell Transplant May Improve Outcomes in PTCL

By

November 17, 2022

Researchers sought to determine whether patients with PTCL who have a complete response after A+CHP would benefit from SCT.

Hematologic Cancers

UCB HSCT May Be Effective Alternative to MS HSCT in Adult B-ALL

By

Andrea S. Blevins Primeau, PhD, MBA

October 31, 2022

Unrelated cord blood transplant can result in comparable outcomes as matched sibling donor transplant in adults with B-cell acute lymphoblastic leukemia.

Lymphoma

Bendamustine-Rituximab Induction Appears Effective in Mantle Cell Lymphoma

By

Jonathan Goodman, MPhil

October 13, 2022

First-line bendamustine plus rituximab followed by ASCT and rituximab maintenance appears effective in mantle cell lymphoma.

Hematologic Cancers

BuCy Noninferior to TBI-Cy for Patients With B-ALL Undergoing Allo-HSCT

By

Lauren Dembeck, PhD

October 5, 2022

BuCy conditioning appears noninferior to TBI-Cy conditioning in patients with B-ALL undergoing HLA-matched allo-HSCT.

Multiple Myeloma

Conditioning Regimens Produce Similar Long-Term Outcomes in Newly Diagnosed Multiple Myeloma

By

Vicki Moore, PhD

September 15, 2022

Conditioning with MEL200 or BUMEL produced similar outcomes at 7 years.

Hematologic Cancers

30-Year Analysis Shows Improvements in Allogeneic HCT for Acute Lymphoblastic Leukemia

By

Vicki Moore, PhD

September 7, 2022

Researchers sought to determine outcomes with allo-HCT in patients with ALL over 30 years.

Hematologic Cancers

GVHD Grade at Diagnosis Correlates With Disease Progression, Overall Survival

By

Vicki Moore, PhD

August 31, 2022

Researchers sought to determine the rate of progression to a higher grade among patients who develop acute GVHD after hematopoietic stem cell transplant.

Pediatric Cancer

Imbruvica Approved for Pediatric Patients With Chronic Graft-vs-Host Disease

By

Brian Park, PharmD

August 26, 2022

The expanded approval was based on data from the phase 1/2 iMAGINE trial.

News, Pediatric Cancer

Chronic GVHD Linked to Nonmalignant Late Effects in Pediatric Cancer Survivors

By

Vicki Moore, PhD

August 16, 2022

Chronic GVHD is associated with nonmalignant late effects, but not subsequent neoplasms, in pediatric cancer survivors.

Hematologic Cancers

PTCy With Tacrolimus Safe, Effective at Reducing GVHD in Older Patients With Hematologic Cancers

By

Jessica Nye, PhD

July 11, 2022

Researchers sought to determine the safety and efficacy of posttransplantation cyclophosphamide with tacrolimus as prophylaxis for GVHD in patients with hematologic cancer after allogeneic hematopoietic cell transplantation.