Hepatocellular Carcinoma Archives - Cancer Therapy Advisor

Statin use in patients with kidney cancer improved cancer-specific survival and overall survival.

Statins Linked to Lower Risk of Liver Cancer in Patients With Hepatitis B/C

By

August 22, 2019

Lipophilic statins were linked to a lower risk of hepatocellular carcinoma and death in a cohort of patients with chronic hepatitis B/C.

Damage or injury to the liver caused by a drug or other agent results in hepatotoxicity. Certain chemotherapy drugs are toxins, which can build up in the body faster than the liver can process them, and ultimately, can result in liver damage.11

Gastrointestinal Cancers

DAAs Cut Deaths in Those Treated for HCV-Related Liver Cancer

August 21, 2019

Findings seen for patients receiving direct-acting antivirals with complete response to liver cancer treatment.

Aspirin and Breast Cancer: What's the Story?

Gastrointestinal Cancers

Aspirin May Improve Liver Function After Embolization of HCC

August 13, 2019

Study suggests aspirin is hepatoprotective, improves survival by reducing liver inflammation.

Gastrointestinal Cancers

Keytruda Plus Lenvima Combo Gets Breakthrough Status for Hepatocellular Carcinoma

By

Brian Park, PharmD

July 25, 2019

The Breakthrough Therapy designation was based on updated interim results from the multicenter, open-label, phase 1b KEYNOTE-524/Study 116 trial.

Gastrointestinal Cancers

Cyramza Approved to Treat Hepatocellular Carcinoma

By

Diana Ernst, RPh

May 13, 2019

The FDA has approved Cyramza (ramucirumab; Lilly) for use as a single agent in the treatment of patients with hepatocellular carcinoma (HCC) who have an alpha fetoprotein (AFP) of ≥400ng/mL and have been treated with sorafenib.

liver affected by cirrhosis and hepatitis

Gastrointestinal Cancers

AGA Clinical Practice Update: DAAs for Hepatitis C and Hepatocellular Cancer

April 22, 2019

The AGA present an updated summary of best practice advice for surveillance of hepatocellular cancer and DAA therapy timing.

Patients with HCC who have advanced on sorafenib have poor prognosis and few additional treatment op

Gastrointestinal Cancers

AFP SPEAR T Cells Deemed Safe in First 2 Treated Patients With Hepatocellular Carcinoma

By

Leah Lawrence

April 19, 2019

This first-in-human trial will enroll up to 24 patients.

A large, long-term study found a 97% event-free survival rate at 18 months.

Gastrointestinal Cancers

Less Postoperative Chemotherapy for Pediatric Hepatoblastoma Has No Effect on Disease Control

By

Leah Lawrence

April 18, 2019

Fewer chemotherapy cycles could decrease long-term morbidity for certain patients.

To help curb drug prices, a consortium of hospital groups recently announced plans to form their own

Gastrointestinal Cancers

Rates of HCV-Related Liver Cancer Deaths Increasing Faster in Individuals With Fewer Years of Education

By

Susan Moench, PhD, PA-C

April 11, 2019

There were more than 30,000 deaths due to liver cancer in the US during 2018.

Lower doses and shorter treatment regimens have the potential to reduce both physical and financial

Gastrointestinal Cancers

Direct-Acting Antiviral Therapy and Recurrence of Hepatitis C-Related Hepatocellular Carcinoma

By

Susan Moench, PhD, PA-C

February 6, 2019

The impact of direct-acting antiviral therapy was investigated in a large cohort of patients in complete remission following treatment of hepatitis C-related HCC.