MET Gene Amplification Found to Be Associated With Adverse Clinicopathological Features in Gallbladder Cancer
In this study, there was no correlation between the presence of MET gene amplification and the presence of MET protein overexpression.
Hepatocellular Carcinoma
Microbiome-Derived Therapy Gets Orphan Drug Status for Hepatocellular Carcinoma
SFA001 blocked the progression of hepatitis B to HCC in transgenic HBX animal models
PHGDH Identified as a Potential Target to Overcome Sorafenib Resistance in HCC
PHGDH may be a possible target for overcoming sorafenib resistance, preclinical evidence suggests.
Upfront RT Plus Nivolumab May Benefit Patients With Unresectable Hepatocellular Carcinoma
The objective response rate as determined by mRECIST criteria was 35%, which was substantially higher than historical controls.
Statins Linked to Lower Risk of Liver Cancer in Patients With Hepatitis B/C
Lipophilic statins were linked to a lower risk of hepatocellular carcinoma and death in a cohort of patients with chronic hepatitis B/C.
DAAs Cut Deaths in Those Treated for HCV-Related Liver Cancer
Findings seen for patients receiving direct-acting antivirals with complete response to liver cancer treatment.
Aspirin May Improve Liver Function After Embolization of HCC
Study suggests aspirin is hepatoprotective, improves survival by reducing liver inflammation.
Keytruda Plus Lenvima Combo Gets Breakthrough Status for Hepatocellular Carcinoma
The Breakthrough Therapy designation was based on updated interim results from the multicenter, open-label, phase 1b KEYNOTE-524/Study 116 trial.
Cyramza Approved to Treat Hepatocellular Carcinoma
The FDA has approved Cyramza (ramucirumab; Lilly) for use as a single agent in the treatment of patients with hepatocellular carcinoma (HCC) who have an alpha fetoprotein (AFP) of ≥400ng/mL and have been treated with sorafenib.
AGA Clinical Practice Update: DAAs for Hepatitis C and Hepatocellular Cancer
The AGA present an updated summary of best practice advice for surveillance of hepatocellular cancer and DAA therapy timing.
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