Cytoreductive Nephrectomy Added to ICI Therapy Ups Survival in mRCC
Use of cytoreductive nephrectomy with an immune checkpoint inhibitor reduced the risk of death by 67%.
Kidney Cancer
Overall Cancer Mortality 18% Higher in American Indians/Alaska Natives
Breast and prostate cancer mortality rates were higher in AIAN individuals than in White individuals, despite lower incidence rates.
Chronic Conditions More Likely Among Survivors of Pediatric Wilms Tumor
Survivors of Wilms tumor are more likely than the general population to experience chronic health conditions, a study suggests.
Proteinuria, AKI With New Tyrosine Kinase Inhibitors Characterized
Proteinuria was more frequent with regorafenib than with axitinib.
Researchers Characterize Gut Microbiome of Patients With mRCC and Sarcopenia
Sarcopenic patients with metastatic renal cell carcinoma have distinct bacterial populations that express metabolic pathways associated with a catabolic state.
Live Bacterial Product Improves Outcomes in Metastatic Renal Cell Carcinoma
CBM588, a live bacterial product, improves the efficacy of first-line treatment with nivolumab and ipilimumab in patients with metastatic renal cell carcinoma, a study suggests.
RCC Trials Use “Potentially Excessive” Exclusion Criteria
Renal cell carcinoma trials conducted in the past 10 years used exclusion criteria deemed potentially excessive by ASCO and FCR.
Characteristics of Renal Cell Carcinoma Differ According to Genetic Ancestry
Among patients with renal cell carcinoma, clinical presentation, extent of disease, and germline and somatic alterations differ according to genetic ancestry.
Lenvatinib Plus Pembrolizumab Improves PFS2, OS in Advanced Renal Cell Carcinoma
Second progression-free survival is significantly longer with lenvatinib-pembrolizumab than with sunitinib in patients with advanced renal cell carcinoma.
Intratumoral Vaccination Does Not Appear to Benefit Patients With mRCC
Adding ilixadencel to treatment with sunitinib does not appear to improve outcomes in patients with metastatic renal cell carcinoma undergoing nephrectomy.
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