Machine-Based CT May Help Identify BAP1 Mutation Status in Clear Cell Renal Cell Carcinoma
The method could more accurately classify patients with clear cell disease.
Kidney Cancer
RCC With Isolated Lymph Node Metastases Has Poor Prognosis After Surgery
Following nephrectomy for renal cell carcinoma with lymph node involvement, patients have a 5-year survival rate of only 28%, a new study found.
Adjuvant Sorafenib Does Not Improve Survival in Renal Cell Carcinoma
Active surveillance remains the standard of care for patients at intermediate or high risk of recurrence following nephrectomy.
Longer Duration of Steroids May Affect Outcomes During Anti-PD-1 Treatment
The use of steroids for the treatment of immune-related adverse events may have survival consequences.
The DYSF Gene and Renal Cell Carcinoma: A New Prognostic Biomarker?
There is great interest in evaluating the link between hypercalcemia and prognosis in ccRCC by researching the genes that influence calcium levels.
Should Age Be a Barrier to Clinical Trial Participation for Older Patients With Metastatic Renal Cell Carcinoma?
A retrospective study compared older patients with mRCC with younger ones to determine if age and potential comorbidities is a barrier to clinical trial participation.
CheckMate 214: Long-Term Results Confirm Superiority of Nivolumab Plus Ipilimumab for mRCC
Superiority of the regimen was shown in intermediate- and poor-risk groups, as well as in intention-to-treat populations.
Elevated NLR Combined With Low Sodium Predicts Worse Survival in RCC
At RCC diagnosis, patients with an neutrophil-lymphocyte ratio (NLR) above 3.0 and concomitant hyponatremia had a significant 2.8-fold increased risk of death compared with those who had an NLR of 3.0 or lower and normal sodium levels, a Danish study found.
Axitinib Did Not Meet Study End Point in mRCC, but Dosing Found Feasible
Although study failed to meet its primary endpoint, the researchers suggest approach could be used in clinical practice.
Looking at Survival Differently in Patients With Metastatic Kidney Cancer
Conditional survival may more accurately assess prognosis than traditional survival for patients with metastatic kidney cancer, but the metric is not without its caveats.
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