Positive Surgical Margins Linked to Worse RCC Recurrence, Survival Rates
Findings may inform treatment decisions after nephrectomy with positive surgical margins.
Diagnosis & Disease Information
RCC Stratification System May Need to Be Refined, Data Suggest
Investigators concluded that pN1 RCC could be stratified into pN1 and pN2, with pN2 conferring a poor prognosis comparable to that of non-metastatic stage IV pN0 disease.
Opioid Prescription Can Be Eliminated After Urologic Cancer Surgery
A protocol for eliminating routine opioid prescription after major urologic cancer surgery was both safe and successful, according to researchers.
Cabozantinib Shows Activity in Advanced RCC After CPI-Based Combinations
Cabozantinib can produce responses in patients with advanced clear cell RCC whose disease progressed on first-line checkpoint inhibitor-based therapy, a phase 2 study suggests.
Adjuvant ICI Therapy Provides DFS Benefit in Certain Patients With RCC
Certain patients with resected renal cell carcinoma may benefit from adjuvant treatment with immune checkpoint inhibitors, a meta-analysis suggests.
Percutaneous Cryoablation vs Partial Nephrectomy for cT1b Renal Tumors
Percutaneous cryoablation for cT1b renal tumors is associated with a higher rate of local disease recurrence compared with partial nephrectomy, new data suggest.
Smaller, Rural Oncology Practices Slower to Adopt Approved Immunotherapies
Some oncology practices are less likely than others to adopt immunotherapies within 2 years of regulatory approval, a study suggests.
Genitourinary Cancer Incidence and Mortality Varies by Region, Race, and Sex
Incidence and mortality rates for major genitourinary cancers differ according to sex, race/ethnicity, and geographic region.
Cytoreductive Nephrectomy Added to ICI Therapy Ups Survival in mRCC
Use of cytoreductive nephrectomy with an immune checkpoint inhibitor reduced the risk of death by 67%.
Overall Cancer Mortality 18% Higher in American Indians/Alaska Natives
Breast and prostate cancer mortality rates were higher in AIAN individuals than in White individuals, despite lower incidence rates.
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