WT1 Correlates With Survival in Intermediate-, Poor-Risk Acute Myeloid Leukemia
Investigators aimed to determine the prognostic value of WT1 expression among patients with AML who were in earlier stages of treatment.
Leukemia
CLL Diagnosis Preceded by Decades of Increased Infection Susceptibility
Infections often precede a formal diagnosis of CLL. Researchers found that antimicrobial use began to rise 6 years prior to CLL diagnosis.
Prior History of SCC Could Be a Red Flag for Development of SCC in the Setting of CLL
In this study, a cohort of patients with newly diagnosed CLL was followed to identify the incidence of SCC skin cancer and its associated risk factors in this population.
Genetic Predisposition for Thromboembolism in Adolescent Acute Lymphoblastic Leukemia
As thromboembolism is a common side effect of ALL treatment, investigators assessed whether its occurrence in ALL and in the general adult population have a shared genetic basis.
Older Patients With Previously Untreated AML May Benefit from Azacitidine, Venetoclax
Even after treatment with hypomethylating agents, older patients with AML still lack positive prognoses but azacitidine with venetoclax shows promise.
Selinexor Produces Responses in HMA-Refractory MDS, Oligoblastic AML
Selinexor yields responses in patients with MDS or oligoblastic AML refractory to hypomethylating agents, with manageable adverse events.
Incorporating Immunotherapy for Relapsed Pediatric Acute Lymphoblastic Leukemia
Immunotherapy is changing the treatment paradigm for pediatric patients with relapsed acute lymphoblastic leukemia.
Real-World Data Show Temporal Trends in Risk of Serious Bacterial Infections in Patients With CLL
These study findings show the risk and incidence of serious bacterial infection and its effect on mortality for patients with CLL.
Risk-Stratified Therapy Reduces Late Morbidity, Mortality in Pediatric Acute Lymphoblastic Leukemia
The implementation of risk-stratified therapy appears to have reduced late morbidity and mortality among survivors of pediatric acute lymphoblastic leukemia.
Venetoclax With Chemotherapy: Promising for Elderly Patients With AML?
Combined with chemotherapy, venetoclax appears to be effective for treating AML among fit elderly patients.
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