Researchers sought to determine whether a reinduction therapy approach using mitoxantrone with clofarabine would be safe and effective for pediatric patients with leukemia.
Real-world data confirmed the efficacy and safety profiles of tisagenlecleucel in patients with relapsed/refractory ALL younger than 3 years old.
Nearly 70% of patients had at least 1 potentially actionable therapeutic target.
Researchers sought to determine whether adding eprenetapopt to maintenance azacitidine after HCT would be effective in patients with AML or MDS.
There was no significant difference in transplant-related mortality or overall survival.
The approach resulted in low rates of graft failure, viral infections, and relapse.
There was no survival improvement with idasanutlin in the overall population or among patients with wild-type TP53.
This weekly series highlights eponyms in oncology. This week, we explore the history and namesakes of Li-Fraumeni syndrome.
Researchers sought to determine gene regulation patterns that may help predict response to CAR-T therapy in patients with acute lymphoblastic leukemia.
CoVac-1, a peptide-based COVID-19 vaccine, induced T-cell responses in patients with B-cell deficiencies.
