Platinum Chemotherapy Appears to Cause Clonal Expansion Leading to Myeloid Neoplasms in Children With Neuroblastoma
Children treated for neuroblastoma developed myeloid neoplasms with specific platinum chemotherapy-associated mutation signatures.
Pediatric Cancer
Racial/Ethnic Differences in Pediatric and AYA Cancer Rates Can Vary Widely by Single Year of Age
Looking at single year of age revealed “substantial” differences.
Early Radiotherapy Preserves Vision in Certain Children With Glioma
Early radiotherapy may preserve visual acuity for certain children with sporadic optic pathway/hypothalamic gliomas.
RB-RECIST Criteria May Improve Retinoblastoma Management: An Interview With Jesse L. Berry, MD
In an international, multicenter collaboration, experts modified the RECIST criteria for use as objective endpoints in clinical trials of retinoblastoma therapies.
Extended Induction Chemotherapy Does Not Improve Survival in High-Risk Neuroblastoma
Researchers found that the therapy did not improve EFS or OS in high-risk patients and also led to an increase in toxic side effects.
Durable B-ALL Control With Allogeneic Transplant After CAR T-Cell Therapy
Investigators sought to assess outcomes following CD19 CAR T-cell therapy in children and young adults who underwent alloHSCT for B-cell acute lymphoblastic leukemia.
Risk Factors for Pediatric Hemorrhagic Cystitis Following HCT
Investigators conducted a study to determine the incidence and clinical course of BK virus hemorrhagic cystitis in children undergoing hematopoietic cell transplantation.
Youth With Cancer May Need Parental Help When Deciding Sperm Banking
After a cancer diagnosis, male adolescents may be unprepared to make decisions about fertility preservation independently and instead need parental involvement.
Socioeconomics Tied to Cognitive Function in Survivors of Childhood Brain Tumors
Researchers hope their findings could lead to targeted interventions to improve cognitive outcomes in pediatric brain tumor survivors from families with low socioeconomic status.
Blinatumomab Improves Outcomes in Children With High-Risk B-ALL
A multicenter, randomized, phase 3 trial compared blinatumomab with intensive multidrug consolidation chemotherapy in children with high-risk, first-relapse B-cell ALL.
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