Orteronel Does Not Improve Overall Survival in Prostate Cancer
Orteronel is likely not effective when compared with recently approved agents, according to researchers.
Prostate Cancer
BRCA1/2 Variants Associated With More Cancers Than Previously Thought
Researchers identified associations between pathogenic variants in BRCA1/2 and 7 cancers.
Benefit of Long-Term ADT Varies by Risk Group in Localized Prostate Cancer
There was no significant benefit with long-term ADT, but researchers said there was a “clinically relevant” benefit in patients with high-risk disease.
Prostate Cancer Biopsy, Diagnoses Down During the Pandemic
Between March 2020 and March 2021, the estimated number of missed prostate cancer diagnoses ranged from 97 cases to 573 cases.
TMB May Help Guide ICI Use in Metastatic Castration-Resistant Prostate Cancer
Immune checkpoint inhibitors were more effective than taxanes in patients with a high tumor mutational burden.
DXA Screening Rate Low Among Older Men Initiating ADT for Prostate Cancer
Study confirms the care gap in bone health management and fracture prevention among older men with prostate cancer receiving androgen deprivation therapy.
Depression, Anxiety Rates High With Androgen Deprivation Therapy for Prostate Cancer
An analysis revealed a link between treatment with androgen deprivation therapy and new diagnoses of incident depression and anxiety in men with prostate cancer.
Perineural Invasion Linked to Biochemical Recurrence After Prostatectomy
Patients with perineural invasion had a 4-fold higher risk of biochemical recurrence.
Lymphopenia Tied to Risk of Infection After Radiotherapy
Measuring lymphocytes during or after radiotherapy could provide useful information about infection risk, according to researchers.
Prostate Cancer PLND Might Be Avoidable in Some With Negative PSMA PET/CT
In patients with high-risk prostate cancer, negative PSMA PET/CT does not permit PLND avoidance, investigators cautioned.
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