Declining Use of Chemotherapy in the Last 2 Weeks of Life for Older Patients With Solid Tumor Cancers
During 2013, only 4.9% of older patients with the specified solid tumor cancers received chemotherapy within the last 14 days of life.
Rectal Cancer
Limited Clinical Benefit for the Combination of TRC102 and Temozolomide in Refractory Colorectal Cancer
The median number of prior treatments for patients with relapsed colorectal cancer enrolled in this phase 2 study was 6.
COLOMATE: Using a Liquid Biopsy in CRC to Select a Molecularly Targeted Therapy
The companion study arms under the COLOMATE trial umbrella will include those that specifically enroll patients with HER2-amplified or EGFR-mutant disease.
Rectal Cancer Treatment Regimens
Get the latest treatment options for rectal cancer, including concurrent chemotherapy and radiotherapy and levoleucovorin plus 5-FU.
Long-Term Surgical Outcomes for Rectal Cancer Survivors Elucidated in Study
Participant characteristics were similar between surgical treatment groups.
Risk of Brain Metastasis in Colorectal Cancer Dependent on Tumor Location and Other Metastatic Sites
In patients with colorectal cancer, rectal tumors and lung metastasis appeared to be linked to an elevated risk for brain cancer.
Adding Oxaliplatin to Capecitabine-Based Chemotherapy, Radiation May Not Improve Survival in Rectal Cancer
Researchers randomly assigned 1090 patients with advanced rectal adenocarcinoma to 5 weeks of preoperative capecitabine-based chemoradiation followed by 6 cycles of capecitabine alone or with oxaliplatin.
Rectal Cancer: Adjuvant Chemotherapy May Improve OS After pCR
After a median follow-up of 3.1 years, patients who received adjuvant chemotherapy had improved rates of survival.
Panitumumab Plus Radiotherapy for Rectal Cancer Fails To Meet Endpoint
Investigators enrolled 98 patients to receive preoperative treatment with intravenous panitumumab plus concurrent radiotherapy.
Rectal Cancer: Complete Radiotherapy Dose Improves Overall Survival
Incomplete neoadjuvant radiotherapy is associated with worse overall survival in patients with locally advanced rectal cancer.
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