Oxaliplatin Added to Standard of Care Therapy Increased Disease-Free Survival for Rectal Cancer
Standard combined modality treatment for locally advanced rectal cancer had less disease-free survival than a new CRO/ARO/AIO-04 regimen.
Rectal Cancer
Statin Use Linked with Lower Mortality after Colorectal Cancer Diagnosis
Cumulative exposure to statins after a diagnosis of colorectal cancer was associated with lower overall mortality.
Possible Link Between rs61764370, Prognosis in Colorectal Cancer
Single nucleotide polymorphism in the let-7 complementary site 6 of KRAS mRNA may be a response biomarker in colorectal cancer.
Colorectal Cancer Death “Hotspots” Indicate Need for Increased Screening in Some Areas
Investigators recommend prioritized screening in certain pockets of the U.S. that are statistically identified as colorectal cancer (CRC) death hotspots.
US State Disparities in Colorectal Cancer Rates
Greater progress in reducing colorectal cancer incidence, mortality rates observed in Northeastern states compared to Southern states.
Variant rs9929218 Linked with Prognosis of Patients with CRC
Patients with colorectal cancer who have the variant rs9929218 at 16q22 are at an increased risk for worse survival.
High-Dose CRT Plus Watchful Waiting May Be Safe Alternative for Distal Rectal Cancer
High-dose chemoradiotherapy and watchful waiting might be safe alternative to abdominoperineal resection for treatment of rectal cancer.
mFOLFOX6 Plus Radiotherapy Results in Higher pCR in Rectal Cancer
mFOLFOX6 administered concurrently with radiation therapy resulted in a higher pathological complete response in rectal cancer.
Do Patients with Locally Advanced Rectal Cancer Benefit from Adjuvant Chemotherapy?
A recent letter in JCO discusses whether patients with locally advanced rectal cancer need adjuvant chemotherapy.
In Rectal Cancer, Laparoscopic Surgery Achieves Similar Survival Rates
Patients with localized rectal cancer may achieve similar survival rates by having minimally invasive laparoscopic surgery.
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