High-Throughput Multichain Immune Repertoire Sequencing for Prediction of Treatment Response in Renal Cell Carcinoma
Next-generation sequencing is being increasingly used to characterize the diversity of T-cell and B-cell receptors in individuals.
Renal Cell Carcinoma
FDA Proposal Threatens Transparency on Cancer Drug Safety and Efficacy
FDA documents have been a trove of information for researchers, leading to new insights about the safety and efficacy of a drug. An FDA proposal could end that.
Machine-Based CT May Help Identify BAP1 Mutation Status in Clear Cell Renal Cell Carcinoma
The method could more accurately classify patients with clear cell disease.
Everyone’s Conflicted: How Open Payments Did Little to Discourage Conflicts of Interest in Oncology
Since its inception, the Open Payments act does not appear to have prompted physicians to accept fewer payments from industry overall.
The Disappointing Reality of Crowdfunding Cancer Care
If crowdfunding doesn’t work, here’s how oncologists can help patients with financial toxicity.
RCC With Isolated Lymph Node Metastases Has Poor Prognosis After Surgery
Following nephrectomy for renal cell carcinoma with lymph node involvement, patients have a 5-year survival rate of only 28%, a new study found.
Adjuvant Sorafenib Does Not Improve Survival in Renal Cell Carcinoma
Active surveillance remains the standard of care for patients at intermediate or high risk of recurrence following nephrectomy.
Longer Duration of Steroids May Affect Outcomes During Anti-PD-1 Treatment
The use of steroids for the treatment of immune-related adverse events may have survival consequences.
Pathologists Need Better Reporting Guidelines for Postneoadjuvant Chemotherapy Specimens
Measuring a tumor’s response to neoadjuvant chemotherapy can be prognostic, providing important clues about a patient’s likely outcome following treatment.
Cognitive Impairment Following Immunotherapy Treatment May Be Underestimated
As more and more patients undergo immunotherapy treatments, understanding possible side effects on cognitive function is an important research gap.
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