Skin Cancer Archives - Cancer Therapy Advisor

CD33 positivity and MPC-1 negativity appear to be associated with worse outcomes in patients with multiple myeloma treated with bortezomib as induction therapy.

Low Incidence of Skin Cancer After Liver Transplant in Non-White Patients

By

April 21, 2021

Because of immunosuppressive therapy following liver transplantation, de novo malignancies can occur, and the most common are skin cancers.

The combination may be an attractive option for some, but further research is needed to target the t

Skin Cancer

Risk for Cutaneous Squamous Cell Carcinoma Increases With Age

By

Christina Bennett, MS

April 15, 2021

Among patients younger than 49 years, those with actinic keratosis had a nearly 7-times greater likelihood of developing cutaneous squamous cell carcinoma than patients without actinic keratosis.

Pilocytic astrocytoma is a slow growing, relatively well-defined tumor that develops in the cerebrum, optic nerve pathways, brain stem, and cerebellum. It occurs most often in children and teens.2

Skin Cancer

Past Decade Has Seen Improved Outcomes in Melanoma Brain Metastasis

By

Colby Stong

April 7, 2021

A team of investigators sought to assess the impact of multimodality, CNS-directed treatments on survival rates in patients with melanoma brain metastasis.

Circulating tumor DNA conveyed prognosis among patients with high-risk stage III melanoma, reinforcing the need to include this measure in clinical trial design.

Skin Cancer

Blood Cell Score for Identifying Aggressive Melanoma

By

Leah Lawrence

March 30, 2021

A team of investigators created the myeloid index score, which captures the prognostic value of blood myeloid cells and may be used in the management of patients with melanoma.

Photomicrograph of a lymph node showing malignant melanoma.

Skin Cancer

Patterns in the Development of Melanoma Across Body Sites

By

Vicki Moore, PhD

March 24, 2021

A team of international researchers sought to confirm a “dual pathway hypothesis” for the development of melanoma.

As post-transplant medications are used to reduce the body’s immune reaction to a foreign organ, the

Skin Cancer

Increased Risk of Skin Cancer Linked to Long-Term Use of Certain Diuretics

By

Christina Bennett, MS

March 19, 2021

A team of investigators sought to assess the relationship between thiazides, thiazide-like diuretics, or calcium channel blockers and the development of basal cell carcinoma, squamous cell carcinoma, or cutaneous malignant melanoma.

Skin Cancer

Immunotherapy May Put Men With Melanoma at Risk for Low Testosterone

By

Christina Bennett, MS

March 18, 2021

A team of investigators sought to assess the impact of immunotherapy for malignant melanoma on testosterone levels, as well as to identify risk factors for low testosterone.

Immunotherapy Increasingly Used in Cancer Care

Skin Cancer

Neoantigen Vaccine for Melanoma Reaches Beyond Its Target

By

Julia Faith Sklar

March 12, 2021

Study reports that a personalized, long-peptide vaccine that can target up to 20 personal neoantigens per patient has been successful in preventing melanoma in patients at high risk for recurrence.

New research shows that B cells — and not just T cells — influence whether patients respond to immunotherapy in melanoma, sarcoma, and kidney cancers.

Skin Cancer

Nomogram Developed to Guide Management of Thin Melanomas

By

Leah Lawrence

March 5, 2021

Using readily available clinicopathologic information, a team of investigators developed a risk calculator to predict disease recurrence in patients with thin melanomas.

Skin Cancer

Cavrotolimod Designated Orphan Drug for Merkel Cell Carcinoma

By

Diana Ernst, RPh

March 4, 2021

Cavrotolimod is a toll-like receptor 9 agonist that is designed to induce anticancer immune responses through proprietary spherical nucleic acid (SNA™) technology.