Management of Ipilimumab-Related Colitis
C. Andrew Kistler, MD, PharmD, RPh, discusses how severe GI symptoms caused by ipilimumab can best be managed.
C. Andrew Kistler, MD, PharmD, RPh, discusses how severe GI symptoms caused by ipilimumab can best be managed.
ImmunoPulse DNA IL-12 electroporation immunotherapy might induce regression or stabilization of previously-untreated distant metastatic melanoma.
Use of infliximab for corticosteroid-refractory ipilimumab-induced colitis in patients with melanoma is safe and effective and does not appear to alter response rate or median overall survival.
The annual incidence of anorectal melanoma is greater in men than in women, but no survival advantage by gender can be detected.
For patients with metastatic melanoma, surgical procedures are prevalent, represent a major component of treatment options, and are costly.
Nab-paclitaxel significantly improved progression-free survival (PFS), the primary end point, when compared with dacarbazine in treatment-naïve patients with metastatic malignant melanoma.
Promotes G2 DNA damage checkpoint silencing; inhibitors sensitize melanoma cells to DNA damage.
Distinguishing morphological of melanoma features include irregular distribution, peripheral location
Advisory Board Member Dr. Farma reviews the current recommendations for using sentinel lymph node biopsy in patients with melanoma.
Inflammation can trigger reversible losses of antigens from melanoma cell surfaces, cloaking tumors from T-cell detection.