Cancer Patients May Be Treated With Drugs That Provide No Benefit
Many cancer patients may be treated with drugs that were granted accelerated approval but do not provide a clinical benefit, a study suggests.
Diagnosis & Disease Information
Treatment for Relapsed SCLC Remains “Area of High Unmet Need”
Researchers found a lack of promising investigational treatments in late-stage development for SCLC in the second-line setting and beyond.
Platinum Agents Appear Interchangeable in Small-Cell Lung Cancer
Carboplatin and cisplatin are interchangeable in patients with limited-stage small-cell lung cancer undergoing chemoradiation, a real-world study suggests.
Adding Serplulimab to Chemotherapy Prolongs Survival in Extensive-Stage Small Cell Lung Cancer
Adding serplulimab to chemotherapy prolonged overall survival in patients with previously untreated, extensive-stage small cell lung cancer.
Risk of Severe Pneumonitis After CCRT in Limited-Stage Small-Cell Lung Cancer
An estimated 3% to 6% of patients with limited-stage small-cell lung cancer develop grade 3-5 pneumonitis after concurrent chemoradiation.
Outcomes Seem No Worse With Stereotactic RT for Brain Mets in SCLC
Survival outcomes for SCLC patients with brain metastases appear comparable with stereotactic radiosurgery and whole brain radiotherapy.
Serplulimab May Improve Outcomes in Extensive-Stage Small Cell Lung Cancer
Serplulimab improved overall survival, progression-free survival, and duration of response.
Tiragolumab Does Not Improve Outcomes in Extensive-Stage Small Cell Lung Cancer
Adding tiragolumab to a 3-drug regimen did not improve progression-free or overall survival.
Adebrelimab Improves PFS, OS in Extensive-Stage Small Cell Lung Cancer
Adding adebrelimab to chemotherapy nearly doubled the 2-year overall survival rate and more than tripled the 1-year progression-free survival rate.
Small-Cell Lung Cancer Patients May Have More Socioeconomic Disadvantages
A greater likelihood of socioeconomic disadvantages may help explain the poor survival outcomes observed in patients with small-cell lung cancer, according to researchers.
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