Most Phase 3 Trials of Newly Diagnosed Glioblastoma Show No Improvement in OS
Most recent phase 3 trials of patients with newly diagnosed glioblastoma have shown no significant improvement in overall survival with the experimental treatment.
Diagnosis & Disease Information
Deaths on the Rise in Patients With Malignant Brain Tumors
Deaths among patients with primary malignant brain tumors are on the rise in the United States, data suggest.
Risk of COVID-19 and Poor Outcomes Not Increased Among Glioma Patients
Patients with glioma do not have an increased risk of SARS-CoV-2 infection or worse outcomes from COVID-19, a single-center study suggests.
Neuroophthalmological Late Effects Common in Pediatric/Adolescent Medulloblastoma
Children and adolescents with medulloblastoma frequently suffer from neuroophthalmological sequelae, a single-center study suggests.
Predicting Outcomes of Regorafenib in Patients With Recurrent Glioblastoma
Researchers say they have identified a molecular signature that can be used to predict outcomes of regorafenib treatment in patients with recurrent glioblastoma.
Novel Agent Plus Radiotherapy Shows Promise in MGMT-Unmethylated Glioblastoma
VAL-083 in combination with radiotherapy is safe and active in patients with newly diagnosed MGMT-unmethylated glioblastoma, a phase 2 trial suggests.
Women With Glioblastoma May Be More Likely to Benefit From Immunotherapy
Among glioblastoma patients, women may derive more benefit from immunotherapy than men, research suggests.
Data Show Similar Patterns of Relapse in Standard- and High-Risk Medulloblastoma
Patterns of relapse are similar in patients with standard-risk and high-risk medulloblastoma, a review suggests.
Some Patients With High-Grade Glioma Continue Using Opioids After Perioperative Period
Nearly a third of patients with high-grade glioma who were prescribed opioids after surgery continued to take them beyond the perioperative setting.
Adding Interferon-α to Temozolomide Prolongs Survival in High-Grade Glioma
Adding interferon-α to adjuvant temozolomide can prolong overall survival in patients with high-grade glioma, a phase 3 trial suggests.
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