Glaucoma Treatments

GLAUCOMA TREATMENTS
Generic Brand Strength Size Form Adult Dose
ALPHA2-AGONISTS
apraclonidine HCl 0.5% 5mL, 10mL soln1 1–2 drops 3 times daily
brimonidine 
tartrate
Alphagan P 0.1%, 0.15% 5mL, 
10mL, 
15mL
soln2 1 drop every 8hrs
ALPHA2-AGONIST + BETA-BLOCKER
brimonidine 
tartrate/ timolol maleate
Combigan 0.2%/
 
0.5%
5mL, 10mL soln1 1 drop every 12hrs
BETA-BLOCKERS
betaxolol HCl 0.5% 5mL, 10mL, 15mL soln1 1–2 drops twice daily
Betoptic S 0.25% 2.5mL, 5mL, 10mL, 15mL susp1 1–2 drops twice daily
carteolol HCl 1% 5mL, 10mL, 15mL soln1 1 drop twice daily
levobunolol HCl Betagan 0.5% 5mL, 10mL, 15mL soln1 1–2 drops once or twice daily
metipranolol HCl Optipranolol 0.3% 5mL, 10mL soln1 1 drop twice daily
timolol hemihydrate Betimol 0.25%, 0.5% 5mL, 10mL, 15mL soln1 1 drop twice daily
timolol maleate Istalol 0.5% 5mL soln1 1 drop once daily in the morning
0.25%, 0.5% 5mL, 10mL soln1 Initially 1 drop of 0.25% twice daily; max 1 drop of 0.5%
twice daily
Timoptic Ocudose 0.25%, 0.5% 60 soln4
Timoptic-XE 0.25%, 0.5% 2.5mL, 5mL gel-forming soln 1 drop once daily
CARBONIC ANHYDRASE INHIBITORS
acetazo
lamide
Diamox Sequels 500mg 100 sust-rel caps 500mg twice daily
brinzolamide Azopt 1% 2.5mL, 5mL, 10mL, 15mL susp1 1 drop 3 times daily
dorzolamide HCl Trusopt 2% 10mL soln1 1 drop 3 times daily
methazo
lamide
25mg, 50mg contact supplier tabs 50–100mg twice to three times daily
CARBONIC ANHYDRASE INHIBITOR + ALPHA-AGONIST
brinzo
lamide/ brimonidine tartrate
Simbrinza 1%/0.2% 8mL susp1 1 drop three times daily
CARBONIC ANHYDRASE INHIBITOR + BETA-BLOCKER
dorzolamide HCl/ timolol 
maleate
Cosopt 2%/0.5% 10mL soln1 1 drop twice daily
Cosopt PF 2%/0.5% 0.2mL soln4
CHOLINERGIC (MIOTIC) AGONISTS
pilocarpine HCl Isopto Carpine 1%, 2%, 4% 15mL soln1 2 drops up to 3–4 times daily or more if needed. Heavily pigmented
irides:
need higher concentrations.
CHOLINESTERASE INHIBITORS
ecothiophate iodide Phospholine Iodide 0.125% 5mL soln 1 drop twice daily, in the AM and at bedtime. Apply finger pressure to inner canthus for 1–2mins after instillation.
PROSTAGLANDIN ANALOGS
bimatoprost Lumigan 0.01%, 0.03% 2.5mL, 5mL, 7.5mL soln1 1 drop once daily in the PM
latanoprost Xalatan 0.005% 2.5mL soln1 1 drop once daily in the PM
Xelpros 0.005% 2.5mL emul
sion
1 drop once daily in the PM
latanoprostene bunod Vyzulta 0.024% 5mL soln1 1 drop once daily in the PM
tafluprost Zioptan 0.0015% 0.3mL soln4 1 drop once daily in the PM
travoprost Travatan Z 0.004% 2.5mL, 5mL soln3 1 drop once daily in the PM
RHO KINASE INHIBITORS
netarsudil Rhopressa 0.02% 2.5mL soln1 1 drop once daily in the PM
Rho Kinase Inhibitor + Prostaglandin Analog
netarsudil/ latanoprost Rocklatan 0.02%/ 0.005% 2.5mL soln1 1 drop once daily in the PM
NOTES

Key: soln = solution;
sust-rel caps = sustained release capsules; susp = suspension

1Contains benzalkonium chloride. May be absorbed by soft contact lenses.

2Contains purite.

3Contains sofZia (boric acid, propylene glycol, sorbitol, zinc chloride).

4Preservative-free.

Not an inclusive list of medications and/or official indications. Please
see drug monograph at www.eMPR.com and/or contact company
for full drug labeling.

(Rev. 7/2019)

This article originally appeared on MPR