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ZEMAIRA
Inborn errors of metabolism
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Drug Name:

ZEMAIRA Rx

Generic Name and Formulations:
Alpha1-proteinase inhibitor (human) 1000mg/vial; pwd for IV infusion after reconstitution; preservative-free.

Company:
CSL Behring, LLC

Therapeutic Use:

Indications for ZEMAIRA:

For chronic augmentation and maintenance therapy in individuals with alpha1-proteinase inhibitor (A1-PI) deficiency and clinical evidence of emphysema.

Adult:

Give by IV infusion at a rate of 0.08mL/kg/min. 60mg/kg once weekly. Monitor infusion rates and clinical state closely during infusion.

Children:

Not established.

Contraindications:

History of anaphylaxis or severe systemic response to A1-PI products. Selective IgA deficiencies who have known antibodies against IgA.

Warnings/Precautions:

Contains human plasma; monitor for possible infection transmission. Risk of circulatory overload. Pregnancy (Cat.C). Nursing mothers.

Adverse Reactions:

Asthenia, inj site pain, dizziness, headache, paresthesia, pruritus; hypersensitivity reactions (discontinue if occur).

How Supplied:

Single-use vial—1 (w. diluent + vented transfer device)


Data provided by MPR.

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